Results 151 to 160 of about 464,312 (316)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Gold Nanoparticle-Biological Molecule Interactions and Catalysis

, 2013
This review gives a brief summary of the field of gold nanoparticle interactions with biological molecules, particularly those with possible catalytic relevance.
Jonathan Heddle
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Asymmetric catalysis in the nanocage of porous materials

, 2012
Asymmetric catalysis in the nanocage of porous ...
杨启华, 李灿
core  

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Outstanding Reviewers for Catalysis Science & Technology in 2023

We would like to take this opportunity to thank all of Catalysis Science & Technology's reviewers for helping to preserve quality and integrity in chemical science literature.
Sub Inorganic Chemistry and Catalysis, Inorganic Chemistry and Catalysis, Weckhuysen, Bert, Southall, Maria   +3 more
core  

Nature Catalysis: Nova subscripció. (Abril 2023)

, 2023
Imatge utilitzada per fer publicitat de novetats del CRAI de la Universitat de Barcelona - Vitrina Abril 2023.El CRAI de la Universitat de Barcelona subscriu des d’aquest any la revista Nature Catalysis, títol que s’afegeix a la col·lecció de més de 90 ...
Universitat de Barcelona. CRAI
core  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Data-driven catalyst design for direct catalytic N2O decomposition

Nature Communications
Catalytic N2O decomposition in the presence of O2 is a key process for addressing environmental challenges, such as greenhouse gas emissions and ozone layer depletion.
Chenxi He, Shinya Mine, Yuan Jing, Tsz Lok Wan, Jialei Zhang, Junxian Qin, Ningqiang Zhang, Koichiro Taketoshi, Akihiko Anzai, Ryo Toyoshima, Hiroshi Kondoh, Ichigaku Takigawa, Ken-ichi Shimizu, Takashi Toyao   +13 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source