Results 221 to 230 of about 433,280 (265)

On the catalytic mechanism of dimeric dUTPases

Biochemical Journal, 2013
The Tritryps Trypanosoma brucei, Trypanosoma cruzi and Leishmania donovani are responsible for great morbidity and mortality in developing countries. Their dimeric dUTPases are members of the all-α NTP pyrophosphohydrolase family and represent promising drug targets due to their essential nature and markedly different structural and biochemical ...
Glyn R, Hemsworth, Dolores, González-Pacanowska, Keith S, Wilson   +2 more
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The catalytic mechanism of the hairpin ribozyme

Biochemical Society Transactions, 2002
Evidence that hairpin ribozymes function in the absence of bivalent cation cofactors suggests that active site nucleobases might participate directly in catalytic chemistry. We have adopted an abasic ribozyme rescue strategy to begin to dissect the roles of specific nucleobases in hairpin ribozyme activity. Loss of one active site nucleobase, G8, could
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Catalytic reactions—I Mechanisms

Talanta, 1970
The mechanisms of some reactions used in catalytic analysis are discussed. The knowledge of the mechanism of a catalytic reaction can help in the development of new catalytic reactions and the choice of optimal conditions, and to show the possibilities for further increases in sensitivity.
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The Catalytic Mechanism of Peroxiredoxins

2007
Peroxiredoxins carry out the efficient reduction of a typically broad range of peroxide substrates through an absolutely conserved, activated cysteine residue within a highly conserved active site pocket structure. Though details of reductive recycling after cysteine sulfenic acid formation at the active site vary among members of different Prx classes,
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The Quasicatalytic Mechanism: A Variation of the Catalytic (EC′) Mechanism

Analytical Chemistry, 2009
The classic electrochemical catalytic mechanism, often referred to as the EC' mechanism, is traditionally represented by the two reactions A + e B (E(A/B)(0), k(A/B)(0), alpha(A/B)) and B + P A + Q (K(eq), k(f), k(b)). Implicit in this mechanism is the additional heterogeneous electron transfer P + e Q (E(P/Q)(0), k(P/Q)(0), alpha(P/Q)).
Stephen W, Feldberg, Jennifer F, Campbell   +1 more
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Structure and Catalytic Mechanism of Heme Oxygenase

ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Masaki, Unno, Toshitaka, Matsui, Masao, Ikeda-Saito   +2 more
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Catalytic mechanism of tyrosinases

Tyrosinases (TYR) play a key role in melanin biosynthesis by catalyzing two reactions: monophenolase and diphenolase activities. Despite low amino acid sequence homology, TYRs from various organisms (from bacteria to humans) have similar active site architectures and catalytic mechanisms. The active site of the TYRs contains two copper ions coordinated
Samaneh, Zolghadri, Ali Akbar, Saboury
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The catalytic mechanism of carbonic anhydrase

Inorganica Chimica Acta, 1983
Abstract Steady-state and equilibrium kinetic studies of the CO2HCO−3 interconversion catalyzed by human carbonic anhydrase II (or C) have led to the proposal of a mechanism scheme (Scheme 1) involving two ionizing groups [1–4]. One of these is probably a zinc-bound H2O molecule ionizing to an OH− ion which can react with CO2 to form zinc-bound HCO ...
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The Catalytic Mechanism of Hamster Dihydroorotase

1995
Dihydroorotase catalyses the third reaction of the pathway for de novo biosynthesis of pyrimidine nucleotides. The reaction catalysed involves an intramolecular ring closure of N-carbamyl-L-aspartate (CA-asp) to form L-dihydroorotate (DHO), a dihydropyrimidine.
N K, Williams, E L, Isaac, Y, Peide, R I, Christopherson   +3 more
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Catalytic RNA: Structure and Mechanism

Biochemical Society Transactions, 1993
The Hopkins Lecturer is given the charge of explaining how advances in other fields of science have had an impact on his or her own field of biochemistry. A moment’s thought revealed that it was not at all difficult to think of examples where other scientific fields have provided necessary groundwork for the study of RNA catalysis or RNA biochemistry ...
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