Results 171 to 180 of about 134,373 (267)

Decellularised Corneal Stromal Lamina With or Without Autologous Adipose‐Derived Adult Stem Cells for Advanced Keratoconus: 1‐Year Results of a Phase I/IIa Clinical Trial

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To report the 1‐year clinical outcomes of decellularised human corneal stromal lamina implantation, with or without autologous adipose‐derived adult stem cells (ADASCs), for advanced keratoconus in a European cohort. Methods In this prospective, randomised Phase I/IIa trial, 10 eyes of 10 patients were allocated to decellularised ...
Hao Zhang   +7 more
wiley   +1 more source

CRB1‐Associated Inherited Retinal Dystrophies: Prospective Natural History Study With 4 Years of Follow‐Up

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background The lack of validated and sensitive clinical endpoints remains a major challenge in the design of gene therapy trials for inherited retinal dystrophies (IRDs). This prospective longitudinal cohort study describes the natural disease progression of IRDs caused by pathogenic mutations in the Crumbs homologue 1 (CRB1) gene, and ...
Jessica S. Karuntu   +15 more
wiley   +1 more source

Prevalence and Pattern of Refractive Errors Among Yanomami Indigenous People in the Brazilian Amazon: A Cross‐Sectional Observational Study

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Refractive errors are the leading cause of preventable visual impairment worldwide, yet data from isolated Indigenous populations remain virtually absent from the global literature. The Yanomami, one of the largest Indigenous peoples in the Americas with recent and limited contact with non‐Indigenous society, have no prior ...
Maria Christina Chagas Ferreira   +2 more
wiley   +1 more source

Are Ocular Markers of Sun Exposure Associated With Skin Cancer? A Cross‐Sectional Analysis of the Busselton Healthy Ageing Study

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Higher past sun or ultraviolet radiation exposure increases the risk of skin cancer and three common ocular findings: pterygium, conjunctival ultraviolet autofluorescence (CUVAF) and myopia. We investigated whether ocular markers of past sun exposure are associated with a history of skin cancer.
Gareth Lingham   +11 more
wiley   +1 more source

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