Results 201 to 210 of about 271,210 (377)

Deep Characterization of Isomerization in the Human Eye Lens Proteome by Crystallin‐Depleted Data‐Independent Acquisition

open access: yesAging Cell, EarlyView.
Long‐lived proteins can undergo spontaneous isomerization over time. By examining proteins in the eye lens, we quantified isomerization at aspartic acid, serine, histidine, and glutamic acid residues and identified both age‐dependent and structure‐dependent correlations.
Evan E. Hubbard   +11 more
wiley   +1 more source

Mechanistic Insights Into 5′‐tiRNA‐His‐GTG Mediated Activation of the JNK Pathway in Skin Photoaging

open access: yesAging Cell, EarlyView.
5′‐tiRNA‐His‐GTG expression level is upregulated in the photoaging cell model. 5′‐tiRNA‐His‐GTG negatively regulates the expression of NUP98, thereby activating the JNK signaling pathway to regulate cell senescence. ABSTRACT UV exposure leads to skin damage, thus inducing skin aging.
Lihao Liu   +10 more
wiley   +1 more source

Relationship between the full‐field stimulus test and self‐reported visual function in patients with retinitis pigmentosa: REPEAT Study report No. 3

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To determine the relationship between the full‐field stimulus test (FST) and self‐reported visual function using the Michigan Retinal Degeneration Questionnaire (MRDQ) in patients with retinitis pigmentosa (RP). Methods In this cross‐sectional study, patients with clinically diagnosed RP (n = 31) performed FST to determine retinal ...
J. S. Karuntu   +2 more
wiley   +1 more source

Self‐perceived and measured visual function, the impact of eye‐disease, wellbeing, social determinants, and personality traits in Swedish 70‐year‐olds–results from the Gothenburg H70 Study

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To explore the potential correlation between subjective and measured visual function, as well as to analyse the influence of eye disease, socioeconomic factors and emotional dimensions. Methods Semi‐structured interviews, physical examinations and functional tests (n = 1203).
Lena Havstam Johansson   +2 more
wiley   +1 more source

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