Results 221 to 230 of about 1,796,179 (342)

Retinal Pigment Epitheliopathy due to Sub‐Optimal Recycling of Vitamin A (RESORVA): A Novel RDH11 ‐Related Phenotype

open access: yesClinical Genetics, Volume 109, Issue 5, Page 972-977, May 2026.
RDH11 is a minor isoenzyme that catalyses the oxidation of 11‐cis‐retinol to 11‐cis‐retinal in the retinal pigment epithelium, alongside RDH5 and RDH10. Biallelic null variants in RDH11 lead to upregulation of RDH5 and RDH10 (transcriptional adaptation), maintaining 11‐cis‐retinal bioavailability, but still causing Retinal Pigment Epitheliopathy due to
Kirk A. J. Stephenson   +11 more
wiley   +1 more source

Economic burden of type 2 diabetes management in France according to clinical characteristics

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4019-4032, May 2026.
Abstract Aim We sought to investigate the treatment, medication patterns, and economic burden of type 2 diabetes (T2D) in France. Materials and Methods This was a descriptive retrospective cross‐sectional study of a representative sample of adults in the national healthcare system claims database in 2022.
Bruno Guerci   +9 more
wiley   +1 more source

Cost‐effectiveness analysis of Dexcom ONE+ real‐time continuous glucose monitoring versus self‐monitoring of blood glucose in people with type 2 diabetes in Aotearoa New Zealand

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4055-4065, May 2026.
Abstract Aims Real‐time continuous glucose monitors (rt‐CGM) have been found effective and economical for the treatment of diabetes in many countries. The objective of this study was to provide a cost‐effectiveness analysis of rt‐CGM versus self‐monitoring of blood glucose (SMBG) from the perspective of a healthcare payer in New Zealand.
Ryan G. Paul   +4 more
wiley   +1 more source

Efficacy and safety of brodalumab in palmoplantar pustulosis: A 68‐week randomized Phase 3 trial

open access: yesJournal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 887-899, May 2026.
This open‐label study is a continuation of the 16‐week double‐blind, Phase 3 trial assessing the efficacy and safety of brodalumab 210 mg subcutaneously, till a 68‐week extension period. Continued improvement was seen in the PPPASI 50/75/90 responses, PPPSI scores, PGA 0/1 responses and DLQI. Abstract Background The efficacy and safety of brodalumab in
Masamoto Murakami   +6 more
wiley   +1 more source

A prospective study of carotenoid intake and risk of cataract extraction in US men.

open access: yesAmerican Journal of Clinical Nutrition, 1999
Lisa E. Brown   +7 more
semanticscholar   +1 more source

Medical Care Output and Productivity [PDF]

open access: yes
David Wilcox   +2 more
core  

A Comparative Analysis of Deep Convolutional Networks for Automated Diagnosis of Retinal Detachment in Dogs

open access: yesVeterinary Ophthalmology, Volume 29, Issue 3, May 2026.
ABSTRACT Objective To compare ImageNet‐pretrained deep convolutional neural networks for automated detection of retinal detachment (RD) in canine fundus photographs. Animals Studied Archived fundus images from 275 dogs. Procedures In this multicenter retrospective study, 2000 color fundus photographs (793 RD; 1207 normal) acquired between 2020 and 2025
Sıtkıcan Okur   +7 more
wiley   +1 more source

Assessment of the Advancement of Alveolar Bone Loss in Canine Patients Receiving Definitive Radiotherapy for Sinonasal Tumors

open access: yesVeterinary Radiology &Ultrasound, Volume 67, Issue 3, May 2026.
ABSTRACT Radiotherapy for the treatment of sinonasal tumors in dogs is generally well tolerated, but the range of long‐term adverse effects remains poorly understood. In people receiving radiation for head and neck tumors, existing dental disease is a predisposing factor for radiation‐induced oral complications that can lead to worsening periodontal ...
Erin Paul‐Stewart   +4 more
wiley   +1 more source

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