Results 261 to 270 of about 1,614,131 (378)

Systemic Toxicity of L‐Mimosine in Rabbits: A Non‐Rodent Model for Safety Assessment

open access: yesJournal of Applied Toxicology, Volume 46, Issue 2, Page 639-651, February 2026.
ABSTRACT L‐mimosine is a non‐protein amino acid primarily found in the Mimosoideae subfamily, with high concentrations in Leucaena leucocephala and Mimosa pudica. These plants are widely used in both human and animal nutrition, as well as in phytotherapeutic applications. While the toxic effects of L‐mimosine have been extensively studied in ruminants,
S. M. Ferreira   +6 more
wiley   +1 more source

LungSurg: A Generative AI System for Segmentation and Phase Classification in Thoracoscopic Lobectomy

open access: yesMedComm, Volume 7, Issue 2, February 2026.
The study introduces LungSurg, an AI system designed to assist in video‐assisted thoracoscopic (VATS) lobectomy for lung cancer by accurately identifying anatomical structures and surgical phases. The system outperforms senior surgeons in anatomical sensitivity and improves surgical residents' skills in phase classification and anatomical ...
Hengrui Liang   +20 more
wiley   +1 more source

Fluoroquinolone‐Associated Psychiatric and Ocular Adverse Events: A Disproportionality Analysis Using Real‐World Data From FAERS (2011–2024)

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
This pharmacovigilance study identifies a wide range of rapid‐onset neuropsychiatric and ocular adverse effects linked to fluoroquinolones (FQ). Disproportionality analysis revealed a disproportionate reporting of suicidal ideation and visual impairment following FQ treatment, emphasizing the urgent need for cautious prescribing and strengthened safety
Hau‐Tak Chau, Ngan Pan Bennett Au
wiley   +1 more source

MSC‐Derived Exosomal lnc‐AGT‐3: A Novel Anti‐Angiogenic Target in Age‐Related Macular Degeneration Through p53 Signaling Pathway

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong   +9 more
wiley   +1 more source

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