Results 291 to 300 of about 1,614,131 (378)

LncRNA DANCR Activates p38/mTOR‐Mediated Autophagy via ANXA2 to Exacerbate Oxygen‐Induced Retinal Neovascularization in Mice

open access: yesThe FASEB Journal, Volume 40, Issue 1, 15 January 2026.
This study reveals that the long non‐coding RNA DANCR drives pathological retinal neovascularization in oxygen‐induced retinopathy via an ANXA2‐dependent p38/MAPK/mTOR autophagy pathway. In hypoxic endothelial cells and a murine OIR model, DANCR promotes angiogenesis.
Yini Wang, Jiale Bai, Shihong Zhao
wiley   +1 more source

Organ‐specific low‐dose assessment in pediatric radiotherapy using nanodot OSL and NTCP modeling: Application to medulloblastoma

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 1, January 2026.
Abstract Background In pediatric radiotherapy, controlling low‐dose exposure is a major challenge, particularly in the treatment of medulloblastoma, where the long life expectancy of young patients makes optimization of radioprotection crucial. Purpose This study provides a comprehensive and quantitative assessment of low‐dose exposure to normal ...
Meriem Tantaoui   +6 more
wiley   +1 more source

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk   +6 more
wiley   +1 more source

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli   +6 more
wiley   +1 more source

Implanted Miniature Light Devices for Phototherapeutics

open access: yesAdvanced Therapeutics, Volume 9, Issue 1, January 2026.
Modern phototherapeutics has many attractive features; however, the shallow penetration of light into skin and tissue is an inherent physical limitation that restricts usage to superficial sites of disease. To mitigate this major problem, researchers and clinicians are actively developing miniature implanted light devices that can be implanted within a
Hailey S. Sanders   +5 more
wiley   +1 more source

OCTA‐Derived Retinal Biomarkers and Infarct Topography Improve Etiologic Classification of Recent Single Subcortical Infarction: A Nomogram Model

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
A nomogram integrating reduced superficial vascular complex density on OCTA with proximal and multi‐slice infarct topography improves differentiation of branch atheromatous disease (BAD) from CSVD‐related lacunar infarction (CSVD‐related LI) in recent single subcortical infarction (RSSI).
Shuai Jiang   +7 more
wiley   +1 more source

Hope Walks: The Impact of Clubfoot Treatment on Human Flourishing in Ethiopia

open access: yesHealth Economics, Volume 35, Issue 1, Page 25-35, January 2026.
ABSTRACT Children born with severe congenital conditions in low‐income countries rank among the most disadvantaged among the global ultra‐poor. We study the impact of clubfoot and its treatment across multiple dimensions of human flourishing on data collected from 564 children in Ethiopia.
Bruce Wydick   +2 more
wiley   +1 more source

Driving Innovation: The Impact of National Health Policies on Optometry Research in East Asia

open access: yesThe International Journal of Health Planning and Management, Volume 41, Issue 1, Page 37-46, January 2026.
ABSTRACT This study examines the optometric research landscape in three East Asian countries—China, Japan, and Korea—analysing how research trends align with each country's national health strategies. By evaluating published articles and reviews from national journals between 2006 March 2025, we identify key areas of focus, including paediatric ...
Jihye Ahn, Moonsung Choi
wiley   +1 more source

Home - About - Disclaimer - Privacy