Results 51 to 60 of about 1,130,426 (288)

Chat Generative Pretrained Transformer to optimize accessibility for cataract surgery postoperative management

The Pan-American Journal of Ophthalmology, 2023
Cataract surgery is one of the most common surgeries (over 3 million cases) in the United States per year. Consequently, there are multiple diverse and unique postoperative questions in the postoperative course following cataract extraction.
Ethan Waisberg, Joshua Ong, Mouayad Masalkhi, Nasif Zaman, Prithul Sarker, Andrew G Lee, Alireza Tavakkoli   +6 more
doaj   +1 more source

The effectiveness of early lens extraction with intraocular lens implantation for the treatment of primary angle-closure glaucoma (EAGLE): study protocol for a randomized controlled trial [PDF]

, 2011
Glaucoma is the leading cause of irreversible blindness. Although primary open-angle glaucoma is more common, primary angle-closure glaucoma (PACG) is more likely to result in irreversible blindness.
Burr, JM, Vale L., Azuara-Blanco, Augusto; id_orcid, Gla, EIA-C, Friedman, D, Jimmy Lai, Cochran C., Ramsay C., Nolan, W, Cochran, C, Ramsay, C, Quayyum Zahidul, Azuara-Blanco A., Aung T., McDonald, A, Cochran, Claire, AzuaraBlanco, A, Zahidul Quayyum, McPherson, Gladys, Ramsay, Craig, Foster P., Friedman David, Lai Jimmy, Norrie, John David Taylor, Cochran Claire, McPherson Gladys, McDonald, Alison, Vale, L, Ramsay Craig, Winnie Nolan, Alison McDonald, Burr J.M., Burr, Jennifer M., Aung Tin, Paul Chew, null null, Azuara-Blanco, A, Quayyum, Z, McPherson, G, Azuara-Blanco, Augusto, Burr, Jennifer M, Quayyum, Zahidul, Effectiveness in Angle-closure Glaucoma of Lens Extraction (EAGL, Lai, Jimmy, Augusto Azuara-Blanco, Tin Aung, Foster, P, Norrie, John, Chew Paul, Burr Jennifer M, Foster, Paul, Effectiveness in Angle-closure Glaucoma of Lens Extraction (EAGLE) Study Group, Claire Cochran, David Friedman, Chew, Paul, Nolan, Winnie, Vale, Luke, Friedman D., Lai, J, Friedman, David, Chew P., McPherson G., Foster Paul, Norrie John, Norrie J., John Norrie, Lai J., Aung, T, Aung, Tin, Vale Luke, Craig Ramsay, Gladys McPherson, Paul Foster, McDonald A., McDonald Alison, Jennifer M Burr, Norrie, J, Chew, P, Nolan Winnie, Luke Vale, Quayyum Z., Nolan W., Azuara-Blanco Augusto   +82 more
core   +2 more sources

ORBIT‐AMD: Ordinal Risk, Bilateral Imaging, and Trajectory Learning for Age‐Related Macular Degeneration in Multi‐Cohorts

Advanced Science, EarlyView.
Eligibility flow and real‐world AMD burden in the UKB retinal imaging cohort and TMUEH external‐validation cohort. Overview of the ORBIT‐AMD architecture, integrating retinal representation pretraining, bilateral eye‐graph modeling and concept bottleneck learning to support ordered risk, bilateral context, interpretable lesion concepts, longitudinal ...
Xuehao Cui, Dejia Wen, Patrick Yu‐Wai‐Man, Xiaorong Li   +3 more
wiley   +1 more source

Deconstruction of Human Age‐Related Cataract Capsules Defines Aging

Advanced Science, EarlyView.
We generate a comprehensive atlas of age‐related cataracts (ARC) at a single‐cell resolution, encompassing three disease states—mild cataract group (Mild), severe cortical cataract group (Severe_C), and severe nuclear cataract group (Severe_N). We find that ARC involves seven distinct lens capsule cell types, with notable differences in cellular ...
Qiaomei Tang, Ziyang Tong, Chunmei Fan, Silong Chen, Jiarui Guo, Jianghua Hu, Ke Yao, Zi Yin, Xiao Chen, Yibo Yu   +9 more
wiley   +1 more source

Endocapsular cataract extraction [PDF]

Eye, 1989
Endocapsular (intercapsular) cataract surgery has recently gained popularity, particularly in Europe. We describe our technique of endocapsular cataract extraction and insertion of an intraocular lens and prospectively compare 93 eyes which underwent endocapsular cataract extraction with 83 which underwent a standard extracapsular procedure.
P H, Rosen, J M, Twomey, C M, Kirkness
openaire   +2 more sources

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

Advanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen, Zhiquan Liu, Wenmin Wang, Qing Wang, Tia J. Kowal, Fan Zhang, Grzegorz Walkiewicz, Faruk Hossen, Herbert M. Lachman, Jinqiong Zhou, Yiting Wang, Yang Sun   +11 more
wiley   +1 more source

Patient and Family Reported Clinical Picture of IRF2BPL‐Related Disorders

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT IRF2BPL‐related disorder is a neurodevelopmental disorder caused by heterozygous variants in the IRF2BPL (Interferon Regulatory Factor 2 Binding Protein‐Like) gene. The few reports available in the literature suggest that common symptoms include developmental delay, intellectual disability, and developmental regression.
Zoe Goldstone‐Joubert, Danielle M. Pascual, Laurie Anne Bailey, Loren D. M. Peña, Paul C. Marcogliese   +4 more
wiley   +1 more source

Comparison of safety and effectiveness between phacoemulsification and suture less small incision procedures in Cataract surgery

Journal of University Medical & Dental College, 2023
BACKGROUND & OBJECTIVE: Cataract is major cause of preventable blindness, worldwide. Phacoemulsification and manual small incision are most common surgical methods of cataract.
Asma Aftab , Imran Khan, Yaseen Lodhi, Marrium Shafi, Saad Rauf Khan   +4 more
doaj   +1 more source

Spectrum of Congenital Anomalies in Myhre Syndrome—Insights Into Effects Brought by Altered TGF‐β Signaling via Gain‐of‐Function Variants in SMAD4

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is a rare genetic disorder characterized by progressive multisystem involvement. Gain‐of‐function missense heterozygous variants affecting the Ile500 residue and Arg496 residue of the SMAD4 gene are implicated in this condition.
Kawmadi Gunawardena, Alessandro De Falco, Deborah Osio, Eleanor Sherlock, Emma Kivuva, Erina Sasaki, Francis H. Sansbury, Nayana Lahiri, Patricia Foley, Sahar Mansour, Shane McKee, Tazeen Ashraf, Nicola Brunetti‐Pierri, Usha Kini   +13 more
wiley   +1 more source

Results of Cataract Extraction in Patients with Corneal Opacity

Oftalʹmologiâ, 2019
Purpose. To evaluate the effectiveness of cataract extraction in patients with varying degrees of corneal opacity.Patients and methods. We performed cataract extraction with implantation of the intraocular lenses of 14 eyes (9 patients) with varying ...
E. A. Ivachev, E. V. Anisimova, I. P. Denisova   +2 more
doaj   +1 more source