Results 201 to 210 of about 2,605,325 (333)

Low‐Cost New Glaucoma Drainage Device in Indonesia: One Year Follow‐Up of 252 Subjects

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To evaluate the early efficacy and safety of a new polymethyl methacrylate 200 mm2 non‐valved glaucoma drainage device (GDD) designed for Indonesian use over a 12 month period. Methods This was a prospective study following subjects with various forms of refractory glaucoma aged ≥ 7 years old followed for 12 months. The subjects had
Virna Dwi Oktariana Asrory   +1 more
wiley   +1 more source

Cataract Surgery in the Small Adult Eye: A Review

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Modern cataract surgery continues to advance, yet intraocular lens (IOL) based surgery in the small adult eye remains challenging. Thorough preoperative assessment and surgical preparation optimise postoperative outcomes in these cases. Advances in IOL power calculation, including artificial intelligence‐driven formulas, improve accuracy ...
Jonathan E. Moore   +2 more
wiley   +1 more source

Evidence on the Use of Topical Ciclosporin for Ocular Surface Disease: A Systematic Review and Meta‐Analysis

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To identify evidence on the use of topical CsA for ocular surface diseases (OSD). Methods A literature search was conducted following the preferred reporting items for systematic reviews and meta‐analyses (PRISMA) through June 2023 via Cochrane Central Registries, Clinical Trials Registry, Grey literature and citation searching ...
Ngozi C. Chidi‐Egboka   +10 more
wiley   +1 more source

Safety of an Intravitreal Bevacizumab Biosimilar (MVASI)

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Intravitreal bevacizumab has been used off‐label to treat multiple ocular conditions for almost two decades. Reference bevacizumab, Avastin, was discontinued in Australia in 2021. A bevacizumab biosimilar, MVASI, was approved by the Therapeutic Goods Administration for the treatment of metastatic cancer in 2020.
Hanru Wang   +8 more
wiley   +1 more source

Adalimumab Monotherapy or Combination Therapy With Methotrexate in Paediatric Uveitis: Data From the AIDA Network Uveitis Registry

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background The study objective was to compare the effectiveness of adalimumab (ADA) in monotherapy and in combination with methotrexate (MTX) for paediatric noninfectious uveitis (NIU). Methods Registry‐based observational study. Children receiving ADA for active uveitis were divided into the ADA monotherapy group (group 1) and the ADA plus ...
Carla Gaggiano   +40 more
wiley   +1 more source

Presbyopia Correction in Lens Replacement Surgery: A Review

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Presbyopia affects approximately 1.8 billion individuals globally, posing significant challenges as life expectancy and near‐vision demands, particularly with mobile phone use, grow. Addressing presbyopia during lens replacement surgery has become a key focus for cataract surgeons, aiming to reduce dependence on corrective eyewear. This review
Benjamin Stern, Damien Gatinel
wiley   +1 more source

Long‐Term Morphological Changes of Crosslinked Gelatin Stent

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background This study investigates the long‐term morphological outcomes of crosslinked gelatin stents over a 10‐year period. Methods Participants from the FDA phase 1 and 2 trials for the XEN 140 stent were recalled for follow‐up examinations between 9 and 12 years after their initial implantation.
Yuen Keat Gan   +3 more
wiley   +1 more source

Genotype–Phenotype Correlations, Treatment, and Prognosis of Children With Early‐Onset (Neonatal) Marfan Syndrome

open access: yesClinical Genetics, EarlyView.
Early‐onset Marfan syndrome (eoMFS) is a rare disorder with atrioventricular valve insufficiency being the most severe symptom. We propose to regard eoMFS as a spectrum, ranging from a severe disorder life‐threatening already before or immediately after birth, to a disorder with a better survival rate, creating a window for atrioventricular valve ...
Eva C. van der Leest   +12 more
wiley   +1 more source

Never Late: Cerebrotendinous Xanthomatosis and Improvements in Neurocognitive Functions in an Adult Patient on Chenodeoxycholic Acid Treatment

open access: yesClinical Genetics, EarlyView.
Cerebrotendinous xanthomatosis is due to biallelic pathogenic variants in CYP27A1. We report a new patient and his good neurocognitive outcome on the chenodeoxycholic acid treatment despite therapy starting at the age of 34 years. This highlights the importance of recognizing treatable inherited metabolic diseases at any age.
Randa Sultan   +6 more
wiley   +1 more source

Identification of Genetic Variants Causing Paediatric Cataract in Myanmar

open access: yesClinical Genetics, EarlyView.
Up to 60% of children with cataract in Myanmar have a causative variant in a known cataract gene. This is a similar rate to other populations screened to date, but highlights that there are more cataract genes left to identify. ABSTRACT Genetic testing for paediatric cataract detects a cause in 50%–70% of affected children but is as low as 20% in some ...
Johanna L. Jones   +16 more
wiley   +1 more source

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