Results 31 to 40 of about 281,817 (339)

Comparing the performance of the SF-6D and the EQ-5D in different patient groups [PDF]

open access: yes, 2014
Introduction: This research aims to explore the performance of the SF-6D and the EQ-5D in patients suffering from asthma, chronic obstructive pulmonary disease, cataracts, and rheumatoid arthritis.
Ferreira, Lara N.   +2 more
core   +1 more source

Amyloid found in human cataracts with two-dimensional infrared spectroscopy

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Cataract disease causes blindness in over 18 million people due to aggregation of proteins in the normally clear eye lens. There exist conflicting reports about these aggregates in lens tissue due to complications such as extremely high ...
Ariel M. Alperstein   +3 more
semanticscholar   +1 more source

Effect of plant-based feed ingredients on osmoregulation in the Atlantic salmon lens [PDF]

open access: yes, 2010
Lenses of adult Atlantic salmon fed with a plant oil and plant protein-based diet (plant diet) were compared to lenses of fish fed a diet based on traditional marine ingredients (marine diet) with respect to biochemical composition and functionality ex ...
Baslow   +52 more
core   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

Increased SK3 expression in DM1 lens cells leads to impaired growth through a greater calcium-induced fragility [PDF]

open access: yes, 2006
Although cataract is a characteristic feature of myotonic dystrophy type 1 (DM1), little is known of the underlying mechanisms. We generated four lens epithelial cell lines derived from DM1 cataracts and two from age-matched, non-DM cataracts. Small-pool
Abe   +40 more
core   +2 more sources

Failure of Oxysterols Such as Lanosterol to Restore Lens Clarity from Cataracts

open access: yesScientific Reports, 2019
The paradigm that cataracts are irreversible and that vision from cataracts can only be restored through surgery has recently been challenged by reports that oxysterols such as lanosterol and 25-hydroxycholesterol can restore vision by binding to αB ...
D. Daszynski   +8 more
semanticscholar   +1 more source

Years of sunlight exposure and cataract: a case-control study in a Mediterranean population. [PDF]

open access: yes, 2007
BACKGROUND: We aimed to investigate the relation between sunlight exposure and risk of cataract. METHODS: We carried out a frequency-matched case-control study of 343 cases and 334 controls attending an ophthalmology outpatient clinic at a primary health-
Chaqués-Alepúz, Vicente   +3 more
core   +2 more sources

Drugs associated with cataract formation represent an unmet need in cataract research

open access: yesFrontiers in Medicine, 2022
Decreased light transmittance through the ocular lens, termed cataract, is a leading cause of low vision and blindness worldwide. Cataract causes significantly decreased quality of life, particularly in the elderly.
Jack Carlson   +4 more
doaj   +1 more source

N-acetylhistidine, a novel osmolyte in the lens of Atlantic salmon (Salmo salar L.) [PDF]

open access: yes, 2010
Volume homeostasis is essential for the preservation of lens transparency and this is of particular significance to anadromous fish species where migration from freshwater to seawater presents severe osmotic challenges. In Atlantic salmon (Salmo salar L.)
Bjerkas, Ellen   +4 more
core   +1 more source

Early research on the biological effects of microwave radiation: 1940?1960 [PDF]

open access: yes, 1980
Two overriding considerations shaped the development of early research on the biological effects of microwave radiation?possible medical application (diathermy) and uncertainty about the hazards of exposure to radar.
Cook, HJ   +3 more
core   +1 more source

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