Results 31 to 40 of about 3,580 (214)

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

Diabetes and Cataracts Development—Characteristics, Subtypes and Predictive Modeling Using Machine Learning in Romanian Patients: A Cross-Sectional Study

Medicina
Background and Objectives: Diabetes has become a global epidemic, contributing to significant health challenges due to its complications. Among these, diabetes can affect sight through various mechanisms, emphasizing the importance of early ...
Adriana Ivanescu, Simona Popescu, Adina Braha, Bogdan Timar, Teodora Sorescu, Sandra Lazar, Romulus Timar, Laura Gaita   +7 more
doaj   +1 more source

Associations of Humidity and Temperature With Cataracts Among Older Adults in China

Frontiers in Public Health, 2022
BackgroundThe burden of cataracts was substantial in the current aging world. However, few epidemiological studies have examined the associations between climate and weather conditions and cataract in older populations.
Xiaoyang Lv, Xiangyang Gao, Kejia Hu, Yao Yao, Yi Zeng, Huashuai Chen   +5 more
doaj   +1 more source

Eye‐Brain Neuroimmune Axis Enables Long‐Term Survival in Glioblastoma by Modulating Brain Immune Surveillance and Neuronal Excitability

Advanced Science, EarlyView.
The eye–brain neuroimmune axis triggers immune activation and disrupts pathological neuronal connectivity to extend glioblastoma survival. ABSTRACT As an anatomical extension of the central nervous system (CNS), the eye harbors rich neural and immune interfaces with the brain. However, the integrated immunological and neurological nexus between the eye
Mingyue Cui, Lulu Qian, Binbin Chu, Xuan Qin, Menglin Wu, Minke Wu, Tongyu He, Baochuan Zhang, Bin Song, Yao He   +9 more
wiley   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source

Risk Factors of Cataract Incidence In Patients Men Age 40-55 Years At Pertamina Hospital Balikpapan

Window of Health, 2018
Cataracts occur due to opacities in the lens of the eye resulting in hanging of light into the eyeball, so the vision becomes blurred and over time can cause blindness. One of the most common causes of blindness worldwide is cataracts. Increased cases of
Andi Dewi Sari, Masriadi Masriadi, Arman Arman   +2 more
doaj   +1 more source

Christmas Tree Cataract - A Cataract that Glitters

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2016
A 54-year-old man presented to the Ophthalmology OPD with redness and discharge from his eyes. His vision was 20/20 in both the eyes. There was diffuse conjunctival congestion and mild discharge in both the eyes. On detailed examination, the left eye showed highly refractive, multi-coloured, iridescent crystals in the inferior cortex and nucleus of the
Tanie Natung, Lanalyn Thangkhiew, Avonuo Keditsu, Wakaru Shullai   +3 more
openaire   +3 more sources

ORBIT‐AMD: Ordinal Risk, Bilateral Imaging, and Trajectory Learning for Age‐Related Macular Degeneration in Multi‐Cohorts

Advanced Science, EarlyView.
Eligibility flow and real‐world AMD burden in the UKB retinal imaging cohort and TMUEH external‐validation cohort. Overview of the ORBIT‐AMD architecture, integrating retinal representation pretraining, bilateral eye‐graph modeling and concept bottleneck learning to support ordered risk, bilateral context, interpretable lesion concepts, longitudinal ...
Xuehao Cui, Dejia Wen, Patrick Yu‐Wai‐Man, Xiaorong Li   +3 more
wiley   +1 more source

Gender Differences in the Association Between Cataract and Mental Health in Adults With Diabetes: A Cross-Sectional Analysis From the Spanish National Health Survey 2017

Frontiers in Public Health, 2021
Objective: This study aimed to explore gender differences in the associations between cataracts and self-reported depression and chronic anxiety in Spanish adults with diabetes.Methods: Cross-sectional data from the Spanish Health Survey 2017 were ...
Guillermo F. López Sánchez, Lee Smith, Louis Jacob, Louis Jacob, Jae Il Shin, Ai Koyanagi, Ai Koyanagi, Shahina Pardhan   +7 more
doaj   +1 more source

Diabetic Retinopathy Classification With Convolutional Neural Networks Designed by the Fuzzy Grey Wolf Optimizer With Parameter Adaptation

AI &Innovation, EarlyView.
ABSTRACT The detection and classification of diseases have become a field of interest for artificial intelligence in recent years, where the development of methods and models that allow support for specialists in different health fields has allowed early detection of diseases and the provision of timely treatment to patients.
Rodrigo Cordero‐Martínez, Daniela Sánchez, Patricia Melin   +2 more
wiley   +1 more source