Results 31 to 40 of about 64,976 (308)

Prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus: A 10-year clinical study (2009-2019)

Open Veterinary Journal, 2023
Background: Although ocular findings in diabetic patients are well described, prevalence data for those is unknown. Aim: To describe the prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus.
Francisco Cantero, Ángel Ortilles, M. Teresa-Peña, Marta Leiva   +3 more
doaj   +1 more source

Effects of Gold Nanoparticles Phytoreduced with Rutin in an Early Rat Model of Diabetic Retinopathy and Cataracts

Metabolites, 2023
Diabetic retinopathy (DR) and cataracts (CA) have an early onset in diabetes mellitus (DM) due to the redox imbalance and inflammation triggered by hyperglycaemia. Plant-based therapies are characterised by low tissue bioavailability.
Mădălina Moldovan, Ana-Maria Păpurică, Mara Muntean, Raluca Maria Bungărdean, Dan Gheban, Bianca Moldovan, Gabriel Katona, Luminița David, Gabriela Adriana Filip   +8 more
doaj   +1 more source

Gamma-D crystallin gene (CRYGD) mutation causes autosomal dominant congenital cerulean cataracts

, 2003
Congenital cataracts are a major cause of bilateral visual impairment in childhood. We mapped the gene responsible for autosomal congenital cerulean cataracts to chromosome 2q33-35 in a four generation family of Moroccan descent. The maximum lod score (7.
Basak, A, Hilal, L., Cherif Chefchaouni, M., Slingsby, Christine, Hajaji, Y, Basak, Ajit K., Arbogast, L., Abitbol, Marc, M, Nandrot, E., Cherif-Chefchaouni, M, Benazzouz, B, Boutayeb, S, Boutayeb, S., Berraho, A., Hilal, Latifa, Abitbol, M., Arbogast, Laurence, Hajaji, Y., Gribouval, O., Benazzouz, B., Abitbol, Marc,, Nandrot, Emeline, Gribouval, Olivier   +22 more
core   +1 more source

Classifications of different types of cataracts.

, 2023
Cataracts are the problems associated with the crystallins proteins of the eye lens. Any perturbation in the conformity of these proteins results in a cataract. Age-related cataract is the most common type among all cataracts as it accounts for almost 80%
Haris Khurram (13945143), Madeeha Fatima (16914171), Saba Zafar (11117843), Muhammad Kamran (692905), Rehan Sadiq Shaikh (16192166), Aqsa Parvaiz (12277749)   +5 more
core   +1 more source

Effect of clinical whole exome sequencing in aetiological investigation and reproductive risk prediction for a couple with monogenic inherited diseases

Frontiers in Genetics
ObjectiveTo determine the genetic causes of monogenic inherited diseases in a couple using clinical whole exome sequencing (WES) and advise on their reproductive choices.MethodsWES was applied to a couple seeking reproductive advice, the female with ...
Yanan Wang, Yuqiong Chai, Jieqiong Wang, Mingya Gao, Weiwei Zang, Yujie Chang   +5 more
doaj   +1 more source

Drugs associated with cataract formation represent an unmet need in cataract research

Frontiers in Medicine, 2022
Decreased light transmittance through the ocular lens, termed cataract, is a leading cause of low vision and blindness worldwide. Cataract causes significantly decreased quality of life, particularly in the elderly.
Jack Carlson, Kate McBride, Kate McBride, Michael O’Connor, Michael O’Connor   +4 more
doaj   +1 more source

Optical properties of artificial intraocular lenses and considerations for additive manufacturing

Frontiers in Medicine
Cataracts, a leading cause of blindness in the world, are commonly treated by replacing the ocular lens with an artificial intraocular lens (IOL).
Bushra Brighesh, Noran Alsuliman, Ahed Nimer, Omnyah Albosaad, Batool Alokosh, Tala Alnaili, Abeer Syed, Michael R. Gardner   +7 more
doaj   +1 more source

Do Connexin Mutants Cause Cataracts by Perturbing Glutathione Levels and Redox Metabolism in the Lens?

Biomolecules, 2020
Cataracts of many different etiologies are associated with oxidation of lens components. The lens is protected by maintenance of a pool of reduced glutathione (GSH) and other antioxidants.
Oscar Jara, Peter J. Minogue, Viviana M. Berthoud, Eric C. Beyer   +3 more
doaj   +1 more source

Features of the Effect of Cataracts and Glaucoma on the Daily Activities of Patients with Sarcopenic Obesity

Oftalʹmologiâ
Age-associated glaucoma and cataracts in combination with sarcopenic obesity, formed mainly against the background of physical inactivity due to vision deficiency, potentially contribute to a decrease in patients’ activity in everyday life, but the ...
O. L. Fabrikantov, A. E. Kopylov, N. M. Agarkov   +2 more
doaj   +1 more source

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

Advanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao, Xiaoyu Li, Hongwei Wang, Zongyi Li, Qun Wang, Yangyang Zhang, Xu Jing, Xia Qi, Qingjun Zhou, Shengqian Dou, Lixin Xie   +10 more
wiley   +1 more source