Results 81 to 90 of about 110,885 (306)

Roles of TGFβ and FGF signals during growth and differentiation of mouse lens epithelial cell in vitro. [PDF]

, 2017
Transforming growth factor β (TGFβ) and fibroblast growth factor (FGF) signaling pathways play important roles in the proliferation and differentiation of lens epithelial cells (LECs) during development.
Gong, Xiaohua, Li, Song, Liu, Kelsey, Wang, Dong, Wang, Eddie, Xia, Chun-Hong   +5 more
core   +2 more sources

The Relationship Between Aldose Reductase and Isoxazole Derivatives: An In Vitro and In Silico Approach to Its Correlation With Diabetic Conditions

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Diabetes mellitus (DM), which can result in a number of problems such as cataracts, neuropathy, retinopathy, nephropathy, and several cardiovascular illnesses, continues to be a growing issue despite major advancements in treatment approaches.
Ahmet Esat Göner, Hatice Esra Duran
wiley   +1 more source

Restoring Glutathione Homeostasis in Glycation-Related Eye Diseases: Mechanistic Insights and Therapeutic Interventions Beyond VEGF Inhibition

Antioxidants
Advanced glycation end-products (AGEs) and oxidative stress are recognized as central contributors to the pathogenesis of age-related or diabetic cataracts, diabetic retinopathy (DR), and age-related macular degeneration (AMD).
Yong Chool Boo
doaj   +1 more source

A novel dominant mutation in CRYAB gene leading to a severe phenotype with childhood onset

Molecular Genetics & Genomic Medicine, 2020
Background αB‐crystallin is a promiscuous protein involved in numerous cell functions. Mutations in CRYAB have been found in patients with different pathological phenotypes that are not properly understood.
Ana T. Marcos, Diego Amorós, Beatriz Muñoz-Cabello, Francisco Galán, Eloy Rivas Infante, Luis Alcaraz‐Mas, José M. Navarro‐Pando   +6 more
doaj   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Features of the Effect of Cataracts and Glaucoma on the Daily Activities of Patients with Sarcopenic Obesity

Oftalʹmologiâ
Age-associated glaucoma and cataracts in combination with sarcopenic obesity, formed mainly against the background of physical inactivity due to vision deficiency, potentially contribute to a decrease in patients’ activity in everyday life, but the ...
O. L. Fabrikantov, A. E. Kopylov, N. M. Agarkov   +2 more
doaj   +1 more source

Intraocular Lens Exchange: Indications, Comparative Outcomes by Technique, and Complications

Clinical Ophthalmology, 2023
Veshesh Patel,1 Parastou Pakravan,1 James Lai,1 Arjun Watane,1,2 Divy Mehra,1 Tiffany Alyssa Eatz,1 Nimesh Patel,1,3 Nicolas A Yannuzzi,1 Jayanth Sridhar1 1Bascom Palmer Eye Institute at the University of Miami Miller School of Medicine, Miami, FL, USA ...
Patel V, Pakravan P, Lai J, Watane A, Mehra D, Eatz TA, Patel N, Yannuzzi NA, Sridhar J   +8 more
doaj  

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Acute Bilateral Uveitis, Hypotony, and Cataracts Associated with Ipilimumab and Nivolumab Therapy: Optical Coherence Tomography Angiography Findings

Case Reports in Ophthalmology, 2020
Immune checkpoint inhibitors are increasingly being used for the treatment of several malignancies. In rare cases, patients develop disabling ophthalmic side effects such as dry eyes, episcleritis, keratitis, uveitis, inflammatory orbitopathy, myasthenia
Jessica C. Lee, Ghadeer Al-Humimat, Karanjit S. Kooner   +2 more
doaj   +1 more source

Aging and Color Vision: A Model Using the Farnsworth‐MUNSELL 100‐Hue Test

Color Research &Application, EarlyView.
ABSTRACT Introduction This study examined the theoretical changes in the FM100 Hue scores induced by age‐related changes in the ocular media transmittance. These changes were analyzed with and without a von Kries‐type chromatic adaptation to determine the role of this adaptation process on age‐related changes in hue discrimination.
Victor Opoku‐Yamoah, Stephen J. Dain, Jeffery K. Hovis   +2 more
wiley   +1 more source