Results 41 to 50 of about 167,032 (284)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Frontiers in Environmental Science, 2023 The integrity and health of the ecosystem is the material basis for the common prosperity of different minority areas. Since the acceleration of social and economic growth in the 21st century, excessive social development has caused ecological imbalance,
Wangying Xie +5 more
doaj +1 more source
Entanglement in quantum catastrophes [PDF]
, 2005 We classify entanglement singularities for various two-mode bosonic systems in terms of catastrophe theory. Employing an abstract phase-space representation, we obtain exact results in limiting cases for the entropy in cusp, butterfly, and two ...
Clive Emary +4 more
core +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Optical catastrophes of the swallowtail and butterfly beams
New Journal of Physics, 2017 We experimentally realize higher-order catastrophic structures in light fields presenting solutions of the paraxial diffraction catastrophe integral. They are determined by potential functions whose singular mapping manifests as caustic hypersurfaces in ...
Alessandro Zannotti +3 more
doaj +1 more source
SN Applied Sciences, 2023 Niumasi Coal Mine (located in Shaodong City, Hunan Province, China) was an important producing area of high-quality coking coal in Hunan Province. After large-scale mining of underground coal seams in the area, there has been a large area of surface ...
Yinghui Li
doaj +1 more source
Topological Theory in Bioconstructivism [PDF]
, 2012 In the essay “Landscapes of Change: Boccioni’s Stati d’animo as a General Theory of Models,” in Assemblage 19, 1992, Sanford Kwinter proposed a number of theoretical models which could be applied to computer-generated forms in Bioconstructivism.
Hendrix, John S
core +1 more source
Arthritis Care &Research, EarlyView.Objective This study aimed to determine if program format (in‐person, virtual, or hybrid) results in differences in 3‐month outcomes of pain, function, quality of life, self‐efficacy, and chair stands in a hip/knee osteoarthritis‐management program. Methods A secondary analysis of the Good Life with osteoArthritis in Denmark (GLA:D) Canada database was
Jill Van Damme +7 more
wiley +1 more source
Tunneling into a Fractional Quantum Hall System and the Infrared Catastrophe
, 2007 We calculate the tunneling density of states of a two-dimensional interacting electron gas in a quantizing magnetic field. We show that the observed pseudogap in the density of states can be understood as the result of an infrared catastrophe in a ...
Geller, Michael R., Patton, Kelly R.
core +1 more source
Arthritis Care &Research, EarlyView.Objective We aimed to test the efficacy of personalized treatment of older veterans with chronic low back pain (CLBP) delivered by Aging Back Clinics (ABCs) as compared with usual care (UC). Methods Two hundred ninety‐nine veterans aged 65 to 89 with CLBP from three Veterans Affairs (VA) medical centers underwent baseline testing, randomization to ABC ...
Debra K. Weiner +9 more
wiley +1 more source