Results 221 to 230 of about 42,684 (308)

The Tree of Life Synagogue Attack: A Terrorist Radicalization Assessment Protocol‐18 Examination of Pre‐Attack Warnings and Post‐Attack Contagion and Copycat Effects

Behavioral Sciences &the Law, EarlyView.
ABSTRACT This is a retrospective case study of an antisemitic lone actor terrorist who completed the deadliest attack against the Jewish community in American history. The analysis through the lens of the Terrorist Radicalization Assessment Protocol (TRAP‐18) finds that 72% of the warning indicators were present, including four proximal warning ...
Molly Amman, Julia Kupper, J. Reid Meloy
wiley   +1 more source

Modeling of Color and Degradation of C‐Phycocyanin Extracted From Arthrospira platensis and Chlorogloeopsis HTF

Chemie Ingenieur Technik, EarlyView.
A nonlinear kinetic model was developed and successfully implemented, which describes the degradation of the protein C‐phycocyanin depending on temperature and pH value. C‐phycocyanin had been extracted from two different cyanobacteria. In addition to protein degradation, the fading of the typical blue color of this protein was included in the model ...
Martina Kießling, Knut Franke, Viggó Marteinsson, René Groben, Volker Heinz, Kemal Aganovic   +5 more
wiley   +1 more source

Mechanical force regulates the inhibitory function of PD-1. [PDF]

EMBO Rep
Chen H, Zhang Y, Cui L, Fan J, Zhu H, Wu S, Zhou H, Zhang Y, Song G, Jiang N, Zhu M, Lou C, Chen W, Lou J.   +13 more
europepmc   +1 more source

Talin1 Adhesion Morphology and Colocalization With Tensin3 Are Largely Unaffected by Polyacrylamide Substrate Stiffness

Cytoskeleton, EarlyView.
ABSTRACT Cells sense the stiffness of their extracellular matrix (ECM) and adapt their behavior accordingly. We investigated how ECM stiffness affects the spatial organization of talin1, a key mechanosensitive focal adhesion protein. Using polyacrylamide (PA) hydrogels with tunable stiffnesses (0.2–188 kPa), we analyzed cell morphology, migration ...
Joanna Hajduk, Patrycja Twardawa, Sylwia Bobis‐Wozowicz, Marta Szewczyk, Zenon Rajfur, Zbigniew Baster   +5 more
wiley   +1 more source

Evaluating the effects of CD8/CD4 on T cell function in terms of TCR-pMHC-coreceptor catch and slip bonds. [PDF]

Front Immunol
Travaglino S, Kazemipour Ashkezari AH, Li M, Watson VE, Cong P, Doudy L, Choi HK, Zhu C.   +7 more
europepmc   +1 more source

Ten‐Year Public Expenditure Savings Associated with TNF Inhibitor Biosimilars under Australia's Pharmaceutical Benefits Scheme

Clinical Pharmacology &Therapeutics, EarlyView.
Biologic therapies are a major and growing driver of pharmaceutical expenditure globally, with tumor necrosis factor (TNF) inhibitors among the most widely used and costly biologics. In Australia, these therapies are funded through the Pharmaceutical Benefits Scheme (PBS), where biosimilars offer lower cost alternatives; however, the long‐term public ...
Chin Hang Yiu, Bella D. Ianni, Richard O. Day, Jacques Raubenheimer, Christine Y. Lu   +4 more
wiley   +1 more source

Second-Language Learning Facilitates Non-Adjacent Dependency Learning: Effects Moderated by Specific Language. [PDF]

Cogn Sci
Lu HS, Mintz TH.
europepmc   +1 more source

Repurposing Registries: Completeness of Real‐World Data for Regulatory and HTA Purposes in Three Cancer‐Focused Registries

Clinical Pharmacology &Therapeutics, EarlyView.
Despite developments in supporting the identification and selection of fit‐for‐purpose registries, a translational gap remains between the original purposes of clinically focused registries and their current and future expected use in policymaking. This study aimed to assess the extent to which cancer‐focused registries collect essential data elements ...
Manon C. Wilpshaar, Doranne Hilarius, Luisa Prada, Ansgar Weltermann, Christine Leopold   +4 more
wiley   +1 more source

Duration of vaccine-induced immunity following MMR2 vaccination in a measles and rubella-eliminated country. [PDF]

Int J Epidemiol
Chun JY, Kim AR, Jeong H, Kim YJ, Kang HJ, Jeong HS, Rhie GE, Jee Y, Kim Y, Lee J.   +9 more
europepmc   +1 more source