Results 201 to 210 of about 3,453,634 (259)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Smartphone-based pupillometry in resource-limited settings: an 'eye-catching' prospect. [PDF]

Brain Spine
Kutum C, Lakhe P.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The Pre-Catching Sperm Technique Increases the Efficiency of the Intracytoplasmic Sperm Injection Method by Improving Fertilization and Blastocyst Formation Rates. [PDF]

J Clin Med
Haering C, Manvelyan E, Coyne K, Hyams LA, Hamrick J, Findley J, Weinerman R, Flyckt R, Kim ST.   +8 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Modeling framework to demonstrate elimination of a vector population: Tsetse elimination in Chad. [PDF]

Proc Natl Acad Sci U S A
Hargrove J, Mahamat MH, Aldjibert M, Yoni W, Signaboubo D, Darnas J, Salou E, Tirados I, Mugenyi A, Barreaux P, Solano P, Barreaux AMG.   +11 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Cognitive, functional and affective effects of a multi-task training in nursing home residents: results from a randomized pilot study. [PDF]

Aging Clin Exp Res
Burgo-Beiro C, Facal D, Dosil-Díaz C, Felpete A, Villamide-Gesto J, Campos-Magdaleno M.   +5 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Comparing methods for catching and crating broiler chicken flocks: A trade-off between animal welfare, ergonomics and economics. [PDF]

Poult Sci
Delanglez F, Watteyn A, Ampe B, Segers V, Garmyn A, Delezie E, Sleeckx N, Kempen I, Demaître N, Van Meirhaeghe H, Antonissen G, Tuyttens FAM.   +11 more
europepmc   +1 more source