Results 261 to 270 of about 78,308 (305)
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Journal of Steroid Biochemistry, 1988
Reaction of estrone-3,4-o-quinone with ethanethiol and glutathione leads to the formation of 4-hydroxyestrone-2-thioethers. Incubations of [1-3H]hydroxyestrone with rat liver microsomes and NADPH in the presence of glutathione results in the formation of 4-hydroxyestrone-S-glutathione with no release of tritium in the water indicating GSH addition to C-
Y J, Abul-Hajj, P L, Cisek
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Reaction of estrone-3,4-o-quinone with ethanethiol and glutathione leads to the formation of 4-hydroxyestrone-2-thioethers. Incubations of [1-3H]hydroxyestrone with rat liver microsomes and NADPH in the presence of glutathione results in the formation of 4-hydroxyestrone-S-glutathione with no release of tritium in the water indicating GSH addition to C-
Y J, Abul-Hajj, P L, Cisek
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Nucleophilic Deoxyfluorination of Catechols
Organic Letters, 2011Nucleophilic deoxyfluorinaiton of one of the two hydroxyl groups of catechols has been developed via the Umpolung concept. This method was successively applied to naturally occurring catechols, such as catechins and dopamine, to produce novel fluorinated analogues.
Hiroyuki, Nemoto +2 more
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Complexes of osmium(VI) with catechol and substituted catechols
Journal of the Chemical Society, Dalton Transactions, 1978Osmium tetraoxide reacts with catechols, R(OH)2-o, to give the tris(catecholato)-species [Os(O2R)3] and the polymers [{OsO(O2R)2}n], while in the presence of pyridine or substituted pyridines (L)trans-[OsO2(O2R)L2] complexes are formed. Reaction of cis-[OsO4(OH)2]2– or trans-[OsO2(OH)4]2– with catechols yields salts of trans-[OsO2(O2R)2]2–.
Alastair J. Nielson, William P. Griffith
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Reactions of 3-ethylcatechol and 3-(methylthio)catechol with catechol dioxygenases
Archives of Biochemistry and Biophysics, 1986The reactions of 3-ethylcatechol and 3-(methylthio)catechol with catechol 1,2-dioxygenase and catechol 2,3-dioxygenase from Pseudomonas putida were examined. Both 3-substituted catechols are oxidized by catechol 2,3-dioxygenase at approximately 30% of the rate observed for catechol oxidation by this enzyme.
R A, Pascal, D S, Huang
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A semiempirical study on inhibition of catechol O-methyltransferase by substituted catechols
Journal of Computer-Aided Molecular Design, 1998Catechol and endogenous catechol derivatives are readily methylated by catechol O-methyltransferase (COMT). In contrast, many catechol derivatives possessing electronegative substituents are potent COMT inhibitors. The X-ray structure of the active site of COMT suggests that the methylation involves a lysine as a general base.
Martti Ovaska, Ari Yliniemelä
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Activity of mushroom tyrosinase on catechol and on a catechol estrogen in an organic solvent
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1993A suspension of tyrosinase-coated glass beads in butanol effectively oxidizes catechol substrate. The enzyme is not soluble in the organic solvent and activity can be stopped by removal of the solid state enzyme after low-speed centrifugation or decantation.
G M, Jacobsohn +2 more
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The Journal of Clinical Endocrinology & Metabolism, 1972
The substrate specificity of the catechol-O-methyltransferase, purified from human liver 380-fold, has been tested with a variety of compounds. Catechol estrogens, as well as catechol amines are methylated to their corresponding monomethyl ethers. The relation of the rates of methylation of catechol estrogens and catechol amines depended on enzyme and ...
PETER BALL +3 more
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The substrate specificity of the catechol-O-methyltransferase, purified from human liver 380-fold, has been tested with a variety of compounds. Catechol estrogens, as well as catechol amines are methylated to their corresponding monomethyl ethers. The relation of the rates of methylation of catechol estrogens and catechol amines depended on enzyme and ...
PETER BALL +3 more
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Site of excretion of catechol and catecholamines: renal metabolism of catechol
American Journal of Physiology-Legacy Content, 1970B, Rennick, A, Quebbemann
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