Results 11 to 20 of about 29,449 (247)

Platelet-mediated metabolism of the common dietary flavonoid, quercetin. [PDF]

, 2010
BACKGROUND: Flavonoid metabolites remain in blood for periods of time potentially long enough to allow interactions with cellular components of this tissue.
Bernice Wright, Jeremy Spencer, Jonathan M. Gibbins, Julie A. Lovegrove, Paul Cobine, Trevor Gibson   +5 more
core   +17 more sources

Differences in MB-COMT DNA methylation in monozygotic twins on phenotypic indicators of impulsivity

Frontiers in Genetics, 2023
Epigenetic modifications of the membrane bound catechol-O-methyltransferase (MB-COMT) gene may affect the enzymatic degradation of dopamine, and consequently, human behavior.
Snežana Smederevac, Lissette Delgado-Cruzata, Dušanka Mitrović, Bojana M. Dinić, Toni-Ann T. Bravo, Maria Delgado, Vojislava Bugarski Ignjatović, Selka Sadiković, Ilija Milovanović, Nataša Vučinić, Bojan Branovački, Mechthild Prinz, Zoran Budimlija, Jelena Kušić‐Tišma, Željka Nikolašević   +14 more
doaj   +1 more source

Interaction of silver nanoparticles with catechol O-methyltransferase: Spectroscopic and simulation analyses

Biochemistry and Biophysics Reports, 2021
Catechol O-methyltransferase, an enzyme involved in the metabolism of catechol containing compounds, catalyzes the transfer of a methyl group between S-adenosylmethionine and the hydroxyl groups of the catechol.
Aminu Usman, Kevin Lobb, Brett I. Pletschke, Christopher G. Whiteley, Brendan S. Wilhelmi   +4 more
doaj   +1 more source

Catechol-O-Methyltransferase [PDF]

, 2020
Peer ...
openaire   +3 more sources

A Missense Variant in COMT Associated with Hearing Loss among Young Adults: The National Longitudinal Study of Adolescent to Adult Health (Add Health)

Biomedicines, 2022
Hearing loss is a major public problem with a heritability of up to 70%. Catechol-O-methyltransferase (COMT) encodes an enzyme that is highly expressed in sensory hair cells of the inner ear.
Chuan-Ming Li, Le Chen, Guanjie Chen, Jianhua Zhang, Howard J. Hoffman   +4 more
doaj   +1 more source

Analgesic Effect of Tramadol Is not Altered by Postoperative Systemic Inflammation after Major Abdominal Surgery

Acta Clinica Croatica, 2021
Tramadol is a commonly used analgesic in intensive care units (ICUs) for acute postoperative pain. Conversion of tramadol into active metabolites may be impaired in inflammatory states. Catechol-O-methyltransferase may influence pain.
Nenad Nešković, Saška Marczi, Dario Mandić, Boris Mraovic, Sonja Škiljić, Gordana Kristek, Hrvoje Vinković, Slavica Kvolik   +7 more
doaj   +1 more source

Association of catechol-O-methyltransferase gene polymorphism with benign prostatic hyperplasia in Babylon Province

Medical Journal of Babylon, 2020
Background: Benign prostatic hyperplasia (BPH) is a common nonmalignant disorder in elderly men. Objectives: The objective of the present study was planned to evaluate the frequency and association of catechol-O-methyltransferase (COMT) gene G↔A (Val 158
Nibras Yahya Hussein, Mufeed J Ewadh, Abdul Razzaq Al-Salman   +2 more
doaj   +1 more source

Evidence for the contribution of COMT gene Val158/108Met polymorphism (rs4680) to working memory training-related prefrontal plasticity. [PDF]

, 2020
BackgroundGenetic factors have been suggested to affect the efficacy of working memory training. However, few studies have attempted to identify the relevant genes.MethodsIn this study, we first performed a randomized controlled trial (RCT) to identify ...
Chen, Chuansheng, Chen, Xiongying, Deng, Xiaoxiang, Dong, Qi, Du, Boqi, Fu, Wenjin, Huang, Ling, Jaeggi, Susanne M, Ji, Feng, Li, Jun, Li, Xiaohong, Li, Yang, Wang, Chuanyue, Xiang, Yu-Tao, Zhang, Qiumei, Zhao, Wan   +15 more
core   +1 more source

A Randomized, Sham‐Controlled Trial of Repetitive Transcranial Magnetic Stimulation Targeting M1 and S2 in Central Poststroke Pain: A Pilot Trial

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Central poststroke pain (CPSP), a neuropathic pain condition, is difficult to treat. Repetitive transcranial magnetic stimulation (rTMS) targeted to the primary motor cortex (M1) can alleviate the condition, but not all patients respond. We aimed to assess a promising alternative rTMS target, the secondary somatosensory cortex (S2),
Juhani Ojala, Jukka Vanhanen, Hanna Harno, Pantelis Lioumis, Selja Vaalto, Mari A. Kaunisto, Jukka Putaala, Marko Kangasniemi, Erika Kirveskari, Jyrki P. Mäkelä, Eija Kalso   +10 more
wiley   +1 more source

HUBUNGAN POLIMORFISME GEN CATECHOL-O-METHYLTRANSFERASE (COMT) VAL158MET DENGAN KEJADIAN MIOMA UTERI PADA ETNIS MELAYU DI SUMATERA SELATAN

JKS (Jurnal Kedokteran Syiah Kuala), 2018
Abstrak. Objektif : Untuk mengetahui distribusi karakteristik sosiodemografi, genotip dan alel polimorfisme gen Catechol-O-Methyltransferase (COMT) Val158Met dengan kejadian mioma uteri pada etnis Melayu di Sumatera Selatan.
Precelia Fransiska, Ferry Yusrizal, Legiran Legiran   +2 more
doaj   +1 more source