The Comparison of Catechol-o-methyltransferase VAL158MET on Schizophrenic Bataknese Patients [PDF]
, 2023 David Erickson Simanjuntak +2 more
openalex +1 more source
Distinction and mutual Influences between Parkinson's Disease‐related and unrelated Chronic Pain
Movement Disorders Clinical Practice, EarlyView.Abstract Background Chronic pain (i.e. > 3 months) is a common nonmotor symptom in patients with Parkinson's disease (PD), but the attribution to PD is critical for further treatment. Objectives We explored the PD Pain Classification System (PD‐PCS) criteria for the diagnosis of PD‐related pain and mutual influences between PD‐related and PD‐unrelated ...
Jonathan Hunger +11 more
wiley +1 more source
Neuropsychiatric Disease and Treatment, 2021 Peiyan Ni,1– 3 Manli Liu,1– 3 Dequan Wang,1– 3 Yang Tian,1– 3 Liansheng Zhao,1– 3 Jinxue Wei,1– 3 Xueli Yu,1– 3 Xueyu Qi,1– 3 Xiaojing Li,1– 3 Hua Yu,1– 3 Rongjun Ni,1– 3 Xiaohong Ma,1 ...
Ni P +15 more
doaj
BMC Rheumatology, 2018 Background Fibromyalgia (FM) is a complex, centralized pain condition that is often difficult to diagnose and treat. FM is considered to have a genetic background due to its familial aggregation and due to findings from multiple candidate-gene studies ...
Chee Lee +4 more
doaj +1 more source
Interactions between variation in candidate genes and environmental factors in the etiology of schizophrenia and bipolar disorder : a systematic review [PDF]
, 2018 Schizophrenia and bipolar disorder (BD) are complex and multidimensional disorders with high heritability rates. The contribution of genetic factors to the etiology of these disorders is increasingly being recognized as the action of multiple risk ...
Frydecka, Dorota +6 more
core
Oppositional COMT Val158Met effects on resting state functional connectivity in adolescents and adults [PDF]
, 2014 © 2014, The Author(s).Prefrontal dopamine levels are relatively increased in adolescence compared to adulthood. Genetic variation of COMT (COMT Val158Met) results in lower enzymatic activity and higher dopamine availability in Met carriers.
Banaschewski, T +37 more
core +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Findings are contradictory regarding changes in the incidence and prevalence of Parkinson's disease (PD) over time; data for other parkinsonian disorders are rare. Objectives To analyze temporal trends in the incidence and prevalence of eight parkinsonisms (PD, MSA, PSP, CBS, DLB, vascular parkinsonism, drug‐induced parkinsonism ...
Sacha E. Gandhi +7 more
wiley +1 more source
Revealing quantum mechanical effects in enzyme catalysis with large-scale electronic structure simulation [PDF]
, 2018 Enzymes have evolved to facilitate challenging reactions at ambient conditions with specificity seldom matched by other catalysts. Computational modeling provides valuable insight into catalytic mechanism, and the large size of enzymes mandates multi ...
Kulik, Heather Janine +5 more
core +2 more sources
Movement Disorders Associated with 22q11.2 Microdeletion: A Scoping Review
Movement Disorders Clinical Practice, EarlyView.Abstract Background Movement disorders have recently emerged as important neurologic manifestations of the 22q11.2 microdeletion that affects nearly one in every 2000 live births. Objective We aimed to map the existing evidence regarding the spectrum, diagnosis and treatment, and etiopathogenesis of movement disorders associated with 22q11.2 ...
Nikolai Gil D. Reyes +6 more
wiley +1 more source
COMT Val 158 Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury [PDF]
, 2017 Mild traumatic brain injury (mTBI) results in variable clinical trajectories and outcomes. The source of variability remains unclear, but may involve genetic variations, such as single nucleotide polymorphisms (SNPs).
Barber, Jason +22 more
core +1 more source