Results 141 to 150 of about 1,120,836 (288)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Using categorical data analyses in suicide research: Considering clinical utility and practicality. [PDF]

Suicide Life Threat Behav, 2021
Mitchell SM, Cero I, Littlefield AK, Brown SL.   +3 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Proposal of a Method for Transferring High-Quality Scientific Literature Data to Virtual Patient Cases Using Categorical Data Generated by Bernoulli-Distributed Random Values: Development and Prototypical Implementation. [PDF]

JMIR Med Educ, 2023
Schmidt C, Kesztyüs D, Haag M, Wilhelm M, Kesztyüs T.   +4 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

CPT: Pharmacometrics & Systems Pharmacology
Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the ...
Fernando Carreño, Rashmi Mehta, Andrea Ribeiro deSouza, Jon Collins, Brandon Swift   +4 more
doaj   +1 more source

Incremental Model Fit Assessment in the Case of Categorical Data: Tucker-Lewis Index for Item Response Theory Modeling. [PDF]

Prev Sci, 2023
Cai L, Chung SW, Lee T.
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Hyperactive Children are at Risk of Dental Caries -An Analytical Study

Journal of Indian Association of Public Health Dentistry, 2013
Background: Attention-deficit/hyperactivity disorder (ADHD) is well recognized in western countries, but there were no much reports of ADHD from India. Aim: To determine the relationship of ADHD with dental caries.
C Jeevika, K Sunayana, Adil Ahmed, Preethi Adusumalli, D Prabu, N Naveen   +5 more
doaj  

Bayesian factor models for multivariate categorical data obtained from questionnaires. [PDF]

J Appl Stat, 2021
Capdeville V, Gonçalves KCM, Pereira JBM.   +2 more
europepmc   +1 more source