Three‐dimensional geometric morphometric analysis of diaphragmatic dome motion in COPD patients
Abstract Diaphragmatic dysfunction is a hallmark of chronic obstructive pulmonary disease (COPD), especially in emphysema, where hyperinflation alters diaphragm geometry and impairs inspiratory mechanics. However, quantitative three‐dimensional (3D) assessments of diaphragmatic dome shape and motion across COPD phenotypes are limited.
José M. López‐Rey +5 more
wiley +1 more source
Altered resting-state prefrontal activity and network topology in adolescents with depression: an fNIRS study. [PDF]
Gui G +9 more
europepmc +1 more source
Objective This study aimed to investigate the mechanisms of immune dysregulation in a pediatric patient with monogenic lupus driven by IKZF1 haploinsufficiency. Methods Peripheral immune cells from a patient with IKZF1 haploinsufficiency, patients with lupus with no currently known genetic mutations, and healthy controls were analyzed using single‐cell
Qi Zheng +6 more
wiley +1 more source
Gaussian Processes for Predictive QSAR Modeling of Chromatographic Processes
ABSTRACT Chromatography is a key unit operation in the biopharmaceutical manufacturing process used for protein purification and polishing. Design and optimization of these processes are resource‐intensive resulting from the complex combinatorial design space.
Harini Narayanan +7 more
wiley +1 more source
Deep generative hidden Markov models for synthetic patient data generation: a novel approach for medical AI research. [PDF]
Momenzadeh M, Oshaghi A.
europepmc +1 more source
Neuronal differentiation and tissue engineering strategies for central neurous system injury repair
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia +9 more
wiley +1 more source
Potentials of ChatGPT in Anatomy Research: A Conversation With ChatGPT. [PDF]
Tigga SR, Saluja S.
europepmc +1 more source
Marine silicon for biomedical sustainability
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han +3 more
wiley +1 more source
Beyond Euclid: an illustrated guide to modern machine learning with geometric, topological, and algebraic structures. [PDF]
Papillon M +10 more
europepmc +1 more source

