Results 21 to 30 of about 4,813 (208)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 2022 This thesis consists in several mathematical approaches to calculation and computation. These concepts, central to mathematics and computer science, are often confounded. However, there is a natural distinction to be made between the two.
Calk, Cameron
core +3 more sources
Order-enriched solid functors [PDF]
, 2019 summary:Order-enriched solid functors, as presented in this paper in two versions, enjoy many of the strong properties of their ordinary counterparts, including the transfer of the existence of weighted (co)limits from their codomains to their domains ...
Sousa, Lurdes, Tholen, Walter
core +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao +6 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.Additive manufacturing provides precise control over the placement of continuous fibres within polymer matrices, enabling customised mechanical performance in composite components. This article explores processing strategies, mechanical testing, and modelling approaches for additive manufactured continuous fibre‐reinforced composites.
Cherian Thomas, Amir Hosein Sakhaei
wiley +1 more source
Engineering and theoretical underpinnings of retrenchment
, 2007 Refinement is reviewed, highlighting in particular the distinction between its use as a specification constructor at a high level, and its use as an implementation mechanism at a low level.
R. Banach +12 more
core +1 more source
Influence of Geometric Design on Mechanical Performance of Auxetic Metastructure
Advanced Engineering Materials, EarlyView.Strategic geometric reinforcement transforms auxetic performance. This study evaluates 3D‐printed arrowhead metastructures, revealing that a modified design with local ring reinforcement suppresses premature failure to achieve superior energy absorption and structural efficiency.
Muhammad Gulzari +3 more
wiley +1 more source
On the reflectiveness of special homogeneous surjections of monoids [PDF]
, 2014 We prove that the so-called special homogeneous surjections are reflective amongst surjective homomorphisms of monoids. To do so, we use a general result in categorical Galois theory, and the recent result that the special homogeneous surjections are the
Montoli, Andrea +5 more
core
Comparison of Triply Periodic Minimal Surface Energy Absorbers Under Uniaxial Compressive Loading
Advanced Engineering Materials, EarlyView.This study investigates LCD 3D printed Triply Periodic Minimal Surface (TPMS) structures as mechanical energy absorbers. By comparing various base designs and layered combinations under uniaxial compression, it identifies that a Diamond‐Gyroid sandwich structure offers superior performance.
Sergej Grednev +2 more
wiley +1 more source