Results 131 to 140 of about 3,252,383 (296)
Tres aproximaciones al mestizaje en América Latina colonial.
Historia Crítica, 2002 Based on the exploration of three approaches to crossbreeding in the colonial history of Latin America: Race Mixture in the History of Latin America by Magnus Mörner, El Mestizaje como Gesta by Juan Olaechea Labayen and El Pensamiento Mestizo by Serge ...
Paola Castaño Rodríguez.
doaj
Applied Categorical Structures, 2015 We define the notion of duality categories as generalization of duality groups. Two examples are treated. The first is the Serre duality in the categories of strict polynomial functors. The second concerns finite complexes. We show in particular that finite Tits buildings are duality categories.
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
[1988] Proceedings. Third Annual Information Symposium on Logic in Computer Science, 1989 A categorical generalisation of the notion of domain, used in denotational semantics, is proposed. The generalized domain is a category of ``structures'' and embeddings which is closed under directed colimits and such that any ``structure'' is the directed colimit of its finite substructures.
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Algebraically coherent categories
, 2015 We call a finitely complete category algebraically coherent if the change-of-base functors of its fibration of points are coherent, which means that they preserve finite limits and jointly strongly epimorphic pairs of arrows.
T. Van der Linden +2 more
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source