Results 241 to 250 of about 1,516,973 (367)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Behavioral and neural aftermath of right inferior frontal cortex disruption on ambiguous vocal emotion decisional processes. [PDF]

Sci Rep
Ceravolo L, Moisa M, Grandjean D, Ruff C, Frühholz S.   +4 more
europepmc   +1 more source

Categorizing Motion: Story-Based Categorizations

Unser Hauptbeitrag ist eine Methode zur Erstellung von Bewegungskategorisierungen (Kap. 8). Wir nennen solche Bewegungskategorisierungen story-based Kategorisierungen (story-based categorizations). Konkret kategorisiert eine story-based Kategorisierung starre Entitäten, die sich unabhängig voneinander bewegen (Abs.
openaire   +3 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

A comparative analysis of blood pressure categorization using 24-hour ambulatory blood pressure monitoring in young women with presumed chronic hypertension with and without a history of pregnancy. [PDF]

AJOG Glob Rep
Gupta S, Knutson Sinaise MR, Zaborek J, Hoppe KK.   +3 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Negative Feedback Does Not Reverse Observationally Acquired Binding and Retrieval Effects: A Failed Replication. [PDF]

J Cogn
Franke K, Rothermund K, Hommel B, Giesen CG.   +3 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Neural Responses to Naturalistic Clips of Behaving Animals in Two Different Task Contexts

Frontiers in Neuroscience, 2018
Samuel A. Nastase, Samuel A. Nastase, Yaroslav O. Halchenko, Andrew C. Connolly, M. Ida Gobbini, M. Ida Gobbini, James V. Haxby   +6 more
doaj   +1 more source

Expectation Exerts Flexible and Context-dependent Influence on Conscious Object Recognition. [PDF]

J Cogn Neurosci
Wu YH, Chen B, He BJ.
europepmc   +1 more source