Results 101 to 110 of about 3,612,301 (282)
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
C*-Algebras over Topological Spaces: The Bootstrap Class
We carefully define and study C*-algebras over topological spaces, possibly non-Hausdorff, and review some relevant results from point-set topology along the way.
Meyer, Ralf, Nest, Ryszard
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
In recent years, change detection (CD) of optical remote sensing images has made remarkable progress through using deep learning. However, current CD deep learning methods are usually improved from the semantic segmentation models, and focus on enhancing
Ling Wan, Ye Tian, Wenchao Kang, Lei Ma
doaj +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Assessments of Climate Literacy and Climate Change Awareness
Climate change has become a serious threat to all humans, with impacts already being felt throughout the planet. One effort in climate change education is to improve students' climate literacy and climate change awareness.
Cincin Cintami +3 more
doaj +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Auditory preattentive processing of Thai vowel change perception in consonant-vowel (CV) syllables [PDF]
Event-related potential (ERP) responses to infrequently presented spoken deviant syllables /pi/ among repetitive standard /pc/ syllables were recorded in Thai subjects who ignored these stimuli while reading books of their choices.
Naiphinich Kotchabhakdi +2 more
doaj
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

