Results 321 to 330 of about 414,710 (373)

Differential Mechanisms of LEF/TCF Family-Dependent Transcriptional Activation by β-Catenin and Plakoglobin

, 2000
Jacob Zhurinsky, Michael Shtutman, Avri Ben-Ze’ev   +2 more
openalex   +1 more source

MiR‐29a/b Suppresses CD8+ T Cell Effector Function and Intestinal Inflammation

Exploration, EarlyView.
Our findings suggest that miR‐29a/b is a critical regulator of CD8+ T cells, possibly via the Ifng‐JAK‐STAT signal in IBD patients and the upregulation of miR‐29a/b relieves the development of significant inflammation in the colon of DSS‐induced colitis‐affected mice.
Yingying Lin, Yuqi Wang, Yuning Zhang, Yao Lu, Juan Chen, Yongting Luo, Jian He, Qingfeng Luo, Heng Quan, Weiru Yu, Yujia Luo, Peng Xue, Yi Xue, Xiaoya Lin, Rui Ding, Lining Chen, Yiran Wang, Zenghui Xia, Liang Zhao, Hao Zhang, Ran Wang, Qingyu Wang, Xifan Wang, Jiaqi Su, Fazheng Ren, Cong Lv, Yixuan Li, Huiyuan Guo   +27 more
wiley   +1 more source

Hypoxia-induced PGK1 expression promotes esophageal squamous cell carcinoma progression via stimulating MYH9-mediated GSK3β/β-catenin signalling. [PDF]

Clin Transl Med
Xu JC, Wu LF, Chen TY, Liu YB, Zhang YF, Zhou PH, Zhang YQ.   +6 more
europepmc   +1 more source

Phenylethanoid Glycosides in Cistanches: Chemistry, Pharmacokinetic, and Antitumor Properties

Food Frontiers, EarlyView.
This review systematically summarizes the representative PhGs found in CH species, their pharmacokinetic parameters, and primary metabolites in humans and rats. Additionally, it examines the antitumor activities of PhGs in CH and their associated signaling pathways against various malignancies.
Jie Li, Xin‐yue Cao, Jun‐lin Lv, He‐meng Zhang, Qing‐yue Liang, Yu‐shan Ren, Jun Tian, Gui‐cheng Dong   +7 more
wiley   +1 more source

Effects of the carcinogen TCDD on δ-catenin stability and tumorigenic potential in prostate cancer cells. [PDF]

Am J Cancer Res
Niu Y, Lee HJ, Chen Z, Kim H, Kim K.
europepmc   +1 more source

The Nutritional and Bioactive Components, Potential Health Function and Comprehensive Utilization of Hawthorn: A Review

Food Frontiers, EarlyView.
This review systematically and comprehensively analyzes hawthorn (Crataegus spp.), covering its bioactive constituents, properties, and processed products. ABSTRACT Hawthorn is widely cultivated in China, with excellent varieties and steadily increasing production.
Wenteng Yang, Quanhong Gao, Kun Ran, Mingyue Jiao, Xiaodan Fu, Zhenlin Han, Chao Liu, Ningyang Li   +7 more
wiley   +1 more source

Wnt/β-catenin activation by mutually exclusive FBXW11 and CTNNB1 hotspot mutations drives salivary basal cell adenoma. [PDF]

Nat Commun
Wong K, Bishop JA, Weinreb I, Motta M, Del Castillo Velasco-Herrera M, Bellacchio E, Ferreira I, van der Weyden L, Boccacino JM, Lauri A, Rotundo G, Ciolfi A, Cheema S, Olvera-León R, Offord V, Droop A, Vermes I, Allgäuer M, Hyrcza M, Anderson E, Smith K, de Saint Aubain N, Mogler C, Stenzinger A, Arends MJ, Brenn T, Tartaglia M, Adams DJ.   +27 more
europepmc   +1 more source

Nanoplatform‐Enabled Genetic Interventions for Central Nervous System Disorders: Advances in Delivery Strategies and Therapeutic Potential

Advanced Genetics, EarlyView.
This review provides a detailed description of gene mutations and epigenetic mechanisms in central nervous system (CNS) disease, strategies for gene therapy, challenges for CNS gene therapy and gene‐drug nanocarriers. This review also summarizes the applications of nanogenetic therapy platforms in CNS diseases (brain tumors, neurodegenerative diseases,
Fuming Liang, Shizhen Cui, Jing Yang, Zhaohui He, Ling Zhu   +4 more
wiley   +1 more source

Matrix metalloproteinase-10 promotes kidney fibrosis by transactivating β-catenin signaling. [PDF]

Cell Death Discov
Sun X, Ren Q, Liu X, Tan H, Zhan Z, Lin E, Long Y, Hong X, Zhou L, Liu Y.   +9 more
europepmc   +1 more source

Polyphyllin I Inhibits the Metastasis of Cervical Cancer Through the Regulation of the β-Catenin Signaling Pathway. [PDF]

Int J Mol Sci
Chai Y, Yu S, Lin G, Luo C, Wang X, Zhang R, Peng J, Zhu Y, Zhang J.   +8 more
europepmc   +1 more source