Results 331 to 340 of about 414,710 (373)

Liver-Directed Gene Therapy Mitigates Early Nephropathy in Murine Glycogen Storage Disease Type Ia. [PDF]

J Inherit Metab Dis
Lee C, Pratap K, Zhang L, Chen HD, Arnaoutova I, Starost MF, Mansfield BC, Chou JY.   +7 more
europepmc   +1 more source

Exploration of the mechanism of Polyphyllin I against hepatocellular carcinoma based on network pharmacology, molecular docking and experimental validation. [PDF]

Discov Oncol
Chen Y, Wang Q, Bian S, Dong J, Xiong J, Le J.   +5 more
europepmc   +1 more source

The relationship between acid-sensing ion channel, ASIC2, and oncogenic β-catenin signaling in ovarian cancer. [PDF]

Sci Rep
Joshi T, Chokshi S, Wilhite A, Singleton MH, Catranis E, Scalici J, Lee KJ.   +6 more
europepmc   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

<i>Ano5</i> Deficiency Leads to Abnormal Bone Formation via miR-34c-5p/KLF4/β-Catenin in Gnathodiaphyseal Dysplasia. [PDF]

Int J Mol Sci
Wang S, Zhang S, Xu H, Zhang M, Liu X, Liu S, Li H, Hu Y.   +7 more
europepmc   +1 more source

SOX10, MITF, and microRNAs: Decoding their interplay in regulating melanoma plasticity

International Journal of Cancer, EarlyView.
Abstract Recent studies show that the dysregulation of the transcription factor SOX10 is essential for the development and progression of melanoma. MicroRNAs (miRNAs) can regulate the expression of transcription factors at the post‐transcriptional level. The interactions between SOX10 and its targeting miRNAs form network motifs such as feedforward and
Xin Lai, Chunyan Luan, Zhesi Zhang, Anja Wessely, Markus V. Heppt, Carola Berking, Julio Vera   +6 more
wiley   +1 more source

Therapeutic potential of isoproterenol in androgenetic alopecia: activation of hair follicle stem cells via the PI3K/AKT/β-Catenin signaling pathway. [PDF]

Stem Cell Res Ther
Zhang J, Peng J, Fan Z, Wang H, Wen L, Miao Y, Chai Y, Hu Z, Chen R.   +8 more
europepmc   +1 more source

Recent advances in understanding the role of Wnt5a in prostate cancer and bone metastasis. [PDF]

Discov Oncol
Xie QY, Zhao GQ, Tang H, Wa QD.
europepmc   +1 more source

Tumor Necrosis Factor-Alpha's Role in the Pathophysiology of Colon Cancer. [PDF]

Diseases
Khan S, Aldawood Y, Shaikh AH, Zobairi A, Nabilah U, Alqahtani HM, Vaali-Mohammed MA.   +6 more
europepmc   +1 more source