Results 141 to 150 of about 60,986 (335)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
, 2002 Excerpt: Within Irish drama of the late 20\u27h century, the use of language as a marker for lrishness begins to shift away from a focus on accents and Hiberno-English, towards a use of language that attempts to actually establish new truths: truths ...
Heininge, Kathleen A.
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Good grief: bereavement literature for young adults and A Monster Calls [PDF]
, 2012 Day, G
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Cocaine + Surfing: Reviewed by Jack Ryan, Gettysburg College
, 2019 If you seek a conclusive answer to the question that seems to anchor Chas Smith\u27s Cocaine + Surfing: A Sordid History of Surfing\u27s Greatest Love Affair, Did surfing and cocaine start together in Peru and never leave each other\u27s embrace?, you ...
Zegarra Evidos, Estefany Betsabeth +1 more
core +1 more source
Retracted: Effect of Observation of Shou Hui Tong Bian Capsule (Polygonum Multiflorum and Aloe-Based Herbal Capsule for Cathartic Effect) in Rapid Rehabilitation of Joint Surgery. [PDF]
Evid Based Complement Alternat Med, 2023 And Alternative Medicine EC.
europepmc +1 more source
The Action of Certain Vegetable Cathartics on the Isolated Centre of a Jelly-Fish (Polyorchis)
, 1907 John MacCallum
openalex +1 more source