Results 121 to 130 of about 12,437 (339)
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
A use case of ChatGPT in a flipped medical terminology course. [PDF]
Korean J Med Educ, 2023 Ahn S.
europepmc +1 more source
Interplay of integrins and selectins in metastasis
Molecular Oncology, EarlyView.Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva +2 more
wiley +1 more source
Management of acute poisoning [PDF]
, 2009 No ...
Tygerberg Poison Information Centre, -
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Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Evaluation of Oriental medicines using a cultured renal epithelial cell line, LLC-PK_1 : Effects of Carthami Flos, Rhei Rhizoma and Astragali Radix [PDF]
, 1998 The effects of Carthami Flos，Rhei Rhizoma and Astragali Radix extract，which have been proved to ameliorate renal failure in rats with glycerol-induced renal failure，were examined in cell culture under three different culture conditions．Rhei Rhizoma ...
CHEN CuiPing +2 more
core +1 more source
Faecal ammonia and pH during lactulose administration in man: comparison with other cathartics
Gut, 1972 L. Agostini +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
The Transfer of Radioiodine Across Placenta and Breast [PDF]
, 1954 Author Institution: Department of Anatomy, The Ohio State University, Columbus ...
Gersten, John
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