Studies of Aloe. VI. Cathartic Effect of Isobarbaloin.
, 1998 Yasuko Ishii +3 more
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THE GREAT THERAPEUTIC IMPORTANCE OF A RATIONAL ADAPTATION OF CATHARTICS TO THE PHYSIOLOGIC FUNCTIONS OF THE GASTRO-INTESTINAL SYSTEM. [PDF]
, 1898 Elisa McDaniel
openalex +1 more source
Doing marketing differently: an artnography of cathartic consumption in trauma [PDF]
, 2022 Shona Bettany
openalex +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
‘Pretty cathartic actually’: Reflections on the attempt to reduce re‐traumatization of researchers and nurses taking part in a longitudinal interview study [PDF]
, 2023 Anna Conolly +6 more
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Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Prevention and Inhibition of Peritonitis with Especial Reference to the Harm Done by Cathartics in Incipient Peritonitis [PDF]
, 1910 A Ochsner
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CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
Molecular Oncology, EarlyView.Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki +2 more
wiley +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source