Results 151 to 160 of about 5,151 (267)

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Effect of 3-Day Linaclotide Administration to Reduce the Polyethylene Glycol Volume for Colonoscopy Bowel Preparation: A Multicenter, Noninferiority, Randomized Controlled Trial. [PDF]

Am J Gastroenterol
Pan P, Chen H, Wang T, Liu K, Tuo B, Wang R, Fu H, Jiang C, Chen L, Zhao Q, Wang W, Chen W, Guo Q, Chen W, Li Y, Tian Z, Feng Z, Yang S, Fan Y, Luan F, Chen Y, Li Z, Bai Y.   +22 more
europepmc   +1 more source

Pathology of Cathartic Colon [PDF]

Proceedings of the Royal Society of Medicine, 1972
openaire   +2 more sources

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Preliminary non-comparative evaluation of an adapted colonoscopy preparation protocol for dogs using sodium picosulphate and magnesium citrate. [PDF]

Vet Rec
Elia da Silva Paranhos J, Guillen Gonçalves de Souza M, Araujo de Sousa D, Costabile Soibelman D, Martins da Costa Ferreira S, da Silva Leite J, Penna B, Reis Ferreira AM.   +7 more
europepmc   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Bowel Preparation for Colonoscopy: The Patient Point of View.

Dig Dis
Tontini G, Spada C, Radaelli F, Testoni PA, Ciprandi G, Vecchi M.   +5 more
europepmc   +1 more source

Clinical application of pre-rehabilitation concept on comfort colonoscopy in Chinese elderly patients: a randomised controlled trial. [PDF]

BMC Gastroenterol
Zhang L, Lv X, Zhu Q, Zhou J, Huang H, Huang Y, Si C.   +6 more
europepmc   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

The effect of preoperative mechanical bowel preparation in paediatric bowel surgery on postoperative wound related complications: A meta-analysis. [PDF]

Int Wound J
Chen M, Lin J, Miao D, Yang X, Feng M, Liu M, Xu L, Lin Q.   +7 more
europepmc   +1 more source