Results 211 to 220 of about 5,075 (267)

Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?

Advanced Biology, EarlyView.
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez, Hao Zhang, Dhananjay Sah, Juan P. Cata   +3 more
wiley   +1 more source

Impact of Bowel Preparation Quality on Colonoscopy Findings and Colorectal Cancer Deaths in a Nation-Wide Colorectal Cancer Screening Program. [PDF]

Am J Gastroenterol
Zessner-Spitzenberg J, Waldmann E, Rockenbauer LM, Klinger A, Klenske E, Penz D, Demschik A, Majcher B, Trauner M, Ferlitsch M.   +9 more
europepmc   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Effect of bowel preparation completion time on bowel cleansing efficacy: Prospective randomized controlled trial of different bowel preparation completion times precolonoscopy. [PDF]

Dig Endosc
Kim HM, Kim HS, An YE, Chang JH, Kim TH, Kim CW, Gweon TG.   +6 more
europepmc   +1 more source

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

Advanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali, Mohamed H. Sherif, Nashwa Barakat, Bassant Yahia, Ahmed A. Shokeir, Basel Sitohy   +5 more
wiley   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source

Impact of mechanical bowel preparation on the gut microbiome of patients undergoing left-sided colorectal cancer surgery: randomized clinical trial. [PDF]

Br J Surg
Žukauskaitė K, Horvath A, Gricius Ž, Kvietkauskas M, Baušys B, Dulskas A, Kuliavas J, Baušys R, Letautienė SR, Vaicekauskaitė I, Sabaliauskaitė R, Baušys A, Stadlbauer V, Jarmalaitė S.   +13 more
europepmc   +1 more source

Mechanisms of Increasing Weld Depth during Temporal Power Modulation in High‐Power Laser Beam Welding

Advanced Engineering Materials, EarlyView.
Temporal power modulation increases weld depth in high‐power laser beam welding of dissimilar round bars by nearly 20% compared to same average continuously welded welding power. The mechanism of action also applies to sheet welding and depends on the inertia of keyhole depth for the modulated laser beam power.
Jan Grajczak, David Reynders, Christian Nowroth, Jens Twiefel, Jörg Wallaschek, Sarah Nothdurft, Jörg Hermsdorf, Stefan Kaierle   +7 more
wiley   +1 more source

Using a Mobile Health App (ColonClean) to Enhance the Effectiveness of Bowel Preparation: Development and Usability Study.

JMIR Hum Factors
Chen HY, Tu MH, Chen MY.
europepmc   +1 more source

Performance of Computer-Aided Detection and Quality of Bowel Preparation: A Comprehensive Analysis of Colonoscopy Outcomes. [PDF]

Dig Dis Sci
Norwood DA, Thakkar S, Cartee A, Sarkis F, Torres-Herman T, Montalvan-Sanchez EE, Russ K, Ajayi-Fox P, Hameed A, Mulki R, Sánchez-Luna SA, Morgan DR, Peter S.   +12 more
europepmc   +1 more source