Results 31 to 40 of about 8,583 (268)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Exposições tóxicas agudas em crianças: um panorama Acute toxic exposure in children: an overview
Jornal de Pediatria, 2005 OBJETIVO: Revisar a literatura das exposições tóxicas em pediatria, excluindo os acidentes por animais peçonhentos. FONTES DE DADOS: Revisão narrativa dos principais trabalhos indexados no MEDLINE, especialmente da última década, incluindo as revisões de
Fábio Bucaretchi, Emílio C. E. Baracat
doaj +1 more source
Mechanical bowel preparation and antimicrobial prophylaxis in elective colorectal surgery in Switzerland—a survey [PDF]
, 2018 Background: The aim of this study was to assess the use of mechanical bowel preparation (MBP) and antimicrobial prophylaxis in elective colorectal surgery in Switzerland.
Ackermann, Christoph +5 more
core
Trepanation practices in Asclepieia: systematizing a neurosurgerical innovation. [PDF]
, 2017 As ancient Greeks started looking for deities that could fulfil the pragmatic needs of common people, local heroes started being mythologized and worshipped through cults. The most widespread such example was Asclepius, possibly a skilled war surgeon who
Kousoulis, AA +3 more
core +2 more sources
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Gut and Liver, 2013 Background/AimsPolyethylene glycol (PEG)-based gut lavage solutions are safe and effective, but require the intake of large volumes of fluid. The use of 2 L PEG plus 45 mL sodium phosphate (PEG2 plus NaP) was compared with 4 L PEG (PEG4) for bowel ...
doaj +1 more source
The Cowl - v.26- n.8 - Mar 14, 1973 [PDF]
, 1973 The Cowl - student newspaper of Providence College. Volume 26, Number 8 - March 14, 1973. 8 pages. Note: The volume number printed on the banner page of this issue (XXVI) duplicates the volume number for 1963-64 academic ...
core +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source