Results 51 to 60 of about 8,483 (312)

Is Admission Serum Sodium Concentration a Clinical Predictor for the Outcome of Therapy in Critically Ill Poisoned Patients? [PDF]

open access: yes, 2015
BACKGROUND Disorders of serum sodium concentration are some of the most electrolyte abnormalities in the intensive care unit (ICU) patients. These disorders adversely affect the function of vital organs and are associated with increased hospital ...
Eizadi-Mood, Nastaran.   +6 more
core   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

The Patient Has the Floor [PDF]

open access: yes, 1966
Address given before the Annual Convocation of the Mayo Graduate School of Medicine, Rochester, Minnesota, on May 28 ...
Cooke, Alistair
core   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

The Cowl - v.26- n.8 - Mar 14, 1973 [PDF]

open access: yes, 1973
The Cowl - student newspaper of Providence College. Volume 26, Number 8 - March 14, 1973. 8 pages. Note: The volume number printed on the banner page of this issue (XXVI) duplicates the volume number for 1963-64 academic ...

core   +1 more source

Cathartes Illiger 1811

open access: yes, 2020
Genus Cathartes Illiger, 1811 Cathartes Illiger, 1811, Prodromus Syst. Mamm. Av., p. 236. Type, by subsequent designation, Vultur aura Linnaeus.
openaire   +2 more sources

Cathartic narratives for chaotic thinking [PDF]

open access: yesCanadian Medical Association Journal, 2016
Two years with severe, chronic lower back pain feels like an eternity, yet people in my pain support group have endured pain for decades. They talk about their losses: employment, education, socializing, marriages, relationships, powerful emotions, spirituality, homes, recreation and freedom ...
openaire   +3 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

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