Results 161 to 170 of about 6,548,214 (253)

Vocational and Educational Outcomes in Adults With Sturge–Weber Syndrome: Preliminary Results From a Clinical Needs Assessment

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective The clinical presentation of Sturge–Weber syndrome (SWS) is highly variable, with seizures during infancy and co‑occurring neurodevelopmental conditions commonly reported. Although these features are known to affect childhood functioning, their relationship to adult vocational and educational outcomes remains poorly understood.
Katharine E. Joslyn   +3 more
wiley   +1 more source

Iron ore tailings as a raw material for Fe-Al coagulant production

open access: yesЗаписки Горного института
The paper presents the results of experimental research into the recovery of Fe-Al coagulant from iron ore tailings (IOTs). The variables investigated in the laboratory tests included sulphuric acid concentration, temperature, leaching time, solid/liquid
Vera A. Matveeva   +2 more
doaj  

A White Paper on Advancing Long‐Acting Therapeutics for Maternal and Pediatric Health by Bridging Gaps in Clinical Research, Access and Regulation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
As use cases for long‐acting therapeutics expand across clinical indications, there is a critical need to ensure the inclusion of women who are pregnant or breastfeeding, infants and children—populations with a historical gap in the availability of interventions already approved for use in adults.
Moherndran Archary   +59 more
wiley   +1 more source

Antiproliferation and Anti-invasion Activity of Binuclear Copper(II) Complex in BRAFi-Resistant Melanoma Cells. [PDF]

open access: yesACS Pharmacol Transl Sci
de Moraes Junior MO   +11 more
europepmc   +1 more source

Tramadol Co‐Administration with Oxycodone or Hydrocodone Increases Opioid Burden without Improving Postoperative Pain Control

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Tramadol is frequently co‐prescribed with oxycodone or hydrocodone after surgery under the assumption that its dual mechanism of action provides an opioid‐sparing benefit. However, evidence supporting this practice is limited and inconsistent. We conducted a secondary analysis of the multicenter IGNITE ADOPT‐PGx pragmatic trial of patients undergoing ...
Noor A. Nahid   +302 more
wiley   +1 more source

Time‐Dependent Bias and Prognostic Confounding in Exposure–Response Analysis of Targeted Therapies: Lessons from Sunitinib in Metastatic Renal Cancer

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Exposure–response (E–R) analyses of sunitinib in metastatic renal cell carcinoma (mRCC) have supported concentration‐guided dose escalation. However, such analyses may be biased when exposure metrics incorporate post‐baseline dose modifications, time‐varying apparent clearance, or baseline factors that influence both pharmacokinetics and clinical ...
Han Liu, Lena E. Friberg
wiley   +1 more source

Exercise-induced anaphylaxis with a cofactor of GIP/GLP-1 receptor agonist: A case report. [PDF]

open access: yesJ Allergy Clin Immunol Glob
Chong AC   +5 more
europepmc   +1 more source

The Governance Gap: Democratizing Drug Development Through Decision Architecture

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Drug development is most exposed to governance failure where it can least afford it, in global health. The field has more predictive power than at any point in its history and roughly the same failure rate it had a decade ago. We argue that this paradox persists because the field has invested heavily in prediction science while neglecting decision ...
Craig R. Rayner   +16 more
wiley   +1 more source

Delirium Prevention in Acute Care Telemetry: An Evidence-Based Practice Project. [PDF]

open access: yesWorldviews Evid Based Nurs
Gray D   +7 more
europepmc   +1 more source

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