Results 121 to 130 of about 98,264 (257)

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

Interdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang, Jiaqi Zhou, Hang Qiao, Yifan Jia, Ling Ye, Zeli Li, Jiahe Ouyang, Haoxian Zhou, Kangxin Zeng, Xuemeng Wang, Yixian Wang, Yang Zhang, Yupeng Zhang, Yizhou Cai, Yutao Hu, Minzhe Zhang, Wenwei Xu, Zhenzhen Wu, Xiaofang Qiu, Li Lin   +19 more
wiley   +1 more source

Prevention of intravascular catheter-related infections-25 years later. [PDF]

Infect Control Hosp Epidemiol
Mermel LA, Buetti N.
europepmc   +1 more source

Adipose‐derived small extracellular vesicles exacerbate microvascular dysfunction in heart failure with preserved ejection fraction via mmu‐miR‐582‐3p‐mediated Rap1b suppression

Interdisciplinary Medicine, EarlyView.
This study reveals that small extracellular vesicles (sEVs) from visceral fat compromise coronary microcirculation in a mouse model of heart failure with preserved ejection fraction (HFpEF). The SGLT2 inhibitor canagliflozin emerges as a therapeutic strategy, improving cardiac function and endothelial health.
Lu Chen, Qiuhan Wang, Mengjia Shen, Mingjue Li, Yingqi Zhu, Cankun Zheng, Siyuan Ma, Hairuo Lin, Xiaokang Fu, Rui Zhang, Jianping Bin, Yulin Liao, Qiancheng Wang   +12 more
wiley   +1 more source

Lymph‐based liquid biopsy: Current progress and future potential

Interdisciplinary Medicine, EarlyView.
Recent evidence under the revised Starling principle indicates that lymph‐based liquid biopsies may offer superior diagnostic performance over blood‐based counterparts in certain clinical scenarios, such as early‐stage solid tumor detection. Currently, various biomarkers within the lymphatic system show significant diagnostic potential for a range of ...
Dongdong Liu, Leheng Cheng, Xiaolin Hu, Sergio Bernardini, Hong Zhang, Ling Zhu, Yang Luo   +6 more
wiley   +1 more source

Oxidative Treatment for Reducing Persistent Populations of Escherichia coli Under Amoxicillin and Gentamicin Pressure

Journal of Biophotonics, EarlyView.
Photodynamic inactivation (PDI) with methylene blue and 660 nm LED enhances antibiotic killing of bacteria, accelerating time‐kill kinetics and reducing the MDK99 compared to antibiotics alone. SEM confirms effective cellular damage, demonstrating that PDI potentiates amoxicillin and gentamicin against tolerant bacterial populations. ABSTRACT Bacterial
Bruna C. Correa, Maria Vitória S. Pereira, Vanderlei S. Bagnato, Kate C. Blanco   +3 more
wiley   +1 more source

Effectiveness of different antibiotic lock solutions on catheter-related infections of hemodialysis patients: a systematic review and meta-analysis. [PDF]

Ann Med
Sarmadi S, Sanaie N, Zare-Kaseb A.
europepmc   +1 more source

Thoracic Ultrasound–Related Management Change: Predictors and the Role of Operator Certification (Secondary Analysis of UltraMAN)

Journal of Clinical Ultrasound, EarlyView.
Thoracic ultrasound frequently altered ICU management decisions. Changes were more likely in patients with cardiovascular disease or hypovolemia and occurred independently of operator certification. These findings support the routine use of TUS in critically ill patients, even when performed by less‐experienced but supervised operators.
Jorge E. Lopez Matta, Micah L. A. Heldeweg, Luigi Pisani, Carlos V. Elzo Kraemer, Stefanie Slot, Mark E. Haaksma, Jasper M. Smit, Amne Mousa, Giovanna Magnesa, Fabrizia Massaro, Hugo R. W. Touw, Viviane Schouten, Pieter R. Tuinman, David J. van Westerloo   +13 more
wiley   +1 more source

Dressing Impregnated with Chlorhexidine and Vancomycin for the Prophylaxis of Central Venous Catheter-Related Infections-A Randomized Trial. [PDF]

Infect Dis Rep
Lessa GC, Zanella CC, Krause GP, Senter AM, Suss PH, Ortis GB, de Moraes TP, Tuon FF.   +7 more
europepmc   +1 more source

A New Antibiotic-Loaded Sol-Gel can Prevent Bacterial Intravenous Catheter-Related Infections. [PDF]

Materials (Basel), 2020
Aguilera-Correa JJ, Vidal-Laso R, Carias-Cálix RA, Toirac B, García-Casas A, Velasco-Rodríguez D, Llamas-Sillero P, Jiménez-Morales A, Esteban J.   +8 more
europepmc   +1 more source

Intravascular Catheter–Related Infections [PDF]

Infection Control & Hospital Epidemiology, 2002
Gina Pugliese, Martin S. Favero
openaire   +1 more source