Results 161 to 170 of about 345,705 (263)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Catheter ablation for idiopathic premature ventricular complexes: a single-centre experience. [PDF]

Br J Cardiol
Sia RI, Sharma A, Gill J, Shetty A, Sugihara C, Behar J, O'Neill M, Wright M, Rinaldi A, Whitaker J.   +9 more
europepmc   +1 more source

Adaptive imatinib regimens can mitigate cumulative toxicity while sustaining hemodynamic benefit: A model‐based simulation of the positioning imatinib for pulmonary arterial hypertension trial

British Journal of Clinical Pharmacology, EarlyView.
ABSTRACT Aims Imatinib improves hemodynamics in pulmonary arterial hypertension (PAH), but dose‐dependent toxicity has limited its clinical development. We aimed to quantify the dose–efficacy–toxicity relationship and evaluate alternative dosing strategies using data from the PIPAH trial.
Medhat M. Said, Robert B. de Mooij, Dian Jiao, Reitze J. Ovelgonne, Rami Biram, Juan Delgado‐SanMartin, Alexander M. K. Rothman, Sofia S. Villar, Andreas A. Roussakis, Jurjan Aman, Ron A. A. Mathôt, Eleonora L. Swart, Martin R. Wilkins, Imke H. Bartelink   +13 more
wiley   +1 more source

Avoiding Cardiac Tamponade During Catheter Ablation: Left Juxtaposition of the Right Atrial Appendage. [PDF]

JACC Case Rep
Yamamoto S, Saito N, Itakura D, Miura F, Nakamura S.   +4 more
europepmc   +1 more source

Compliant hydrogel cuff coating with real‐time pressure monitoring and antibiofilm capabilities for ventilator‐associated pneumonia prophylaxis

BMEMat, EarlyView.
A soft‐compliant hydrogel cuff coating combines real‐time pressure monitoring with intrinsic antibacterial activity for prophylaxis of ventilator‐associated pneumonia. A flexible pressure‐sensing patch is embedded in the coating to enable wireless dynamic monitoring of endotracheal cuff pressure through Bluetooth.
Jin Chai, Yifu Tan, Jiaheng Liang, Shen Liu, Jiabin Zhao, Shanbo Ma, Chunxin Liu, Minghua Du, Mark Selvan, Xiaopeng Shi, Liqiang Song, Peng Li   +11 more
wiley   +1 more source

Advances in Catheter Ablation of Ventricular Tachycardia: Technical Considerations and Contemporary Approaches. [PDF]

Rev Cardiovasc Med
De Marco C, Hadjis A, Saint-Phard W, Raymond JM.   +3 more
europepmc   +1 more source

Hyperbranched poly‐L‐lysine surface‐engineered bioprosthetic heart valves with anti‐calcification, anti‐infection, and durability

BMEMat, EarlyView.
The challenges of bioprosthetic heart valves (BHV) with respect to calcification, infection, and poor durability are tackled by surface engineering of hyperbranched poly‐L‐lysine (HBPL), providing a translational solution to improve long‐term valve performance.
Pai Peng, Dongchao Qiu, Yongyuan Kang, Qiaoxuan Wang, Xuelong Wang, Boyana Parvanova, Miroslav Karabaliev, Changyou Gao   +7 more
wiley   +1 more source

Engineered immunostimulatory H2O2‐producing microreactors driven by yeast as localized living cancer therapeutics

BMEMat, EarlyView.
Engineered yeast microreactors that produce H2O2 within tumors enable selective cancer cell killing while releasing immunostimulatory components, effectively suppressing local tumor growth and activating systemic antitumor immunity, with further efficacy enhanced by anti‐PD‐1 therapy and transarterial embolization.
Wenqian He, Chunjie Wang, Minming Chen, Weihao Yang, Bin Yu, Yuhang Hu, Hengze Ding, Yifan Yan, Zhijuan Yang, Liangzhu Feng   +9 more
wiley   +1 more source

Impact of On-Site Cardiothoracic Surgery Availability on Outcomes of Catheter Ablation for Atrial Fibrillation in the United States. [PDF]

J Cardiovasc Electrophysiol
Agarwal S, Patel H, Asad ZUA, Munir MB, Munoz FD, DeSimone CV, Deshmukh A.   +6 more
europepmc   +1 more source

Circular Economy in the Healthcare Industry: Developing a Circularity Assessment Tool for Complex Medical Devices

Business Strategy and the Environment, EarlyView.
ABSTRACT As the circular economy transition gains traction in the healthcare sector, extending the lifespan of complex medical devices has become a key priority, given their high cost and the challenges associated with their technological sophistication.
Tetiana Shevchenko, Lauren Durivault, Meisam Ranjbari, Zahra Shams Esfandabadi, Bernard Yannou, Robert Heidsieck, Michael Saidani, Ghada Bouillass   +7 more
wiley   +1 more source