Results 81 to 90 of about 49,337 (261)

Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma

Advanced Science, EarlyView.
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba, Jinyoung Park, Achal Duhoon, Cao Thuy Giang Nguyen, Nitu Bhaskar, Sumanta Kumar Karan, Hasan Akbaba, Parbeen Singh, Thi Bao Tram Tran, Yuhui Zhu, Zhiming Li, I'jaaz Muhammad, Xiaojun Zhang, Hoang Quan Truong, A. Daniel Davidar, Elizabeth Schmitzer, Vikas N. Vattipally, Angelica F. Lopez, Patrick Kramer, Victor M. Quiroz, Ben Bykov, Claire Hao, Amir Manbachi, Nicholas Theodore, Joshua C. Doloff, Thanh D. Nguyen   +25 more
wiley   +1 more source

Efficacy and Safety of Catheter Ablation in Very Elderly Patients With Atrial Fibrillation: Short‐ To Mid‐Term Outcomes From a Multicenter Study

Journal of Arrhythmia
Background Catheter ablation has become a cornerstone of atrial fibrillation (AF) treatment. The prevalence of AF increases with age. However, research on catheter ablation in very elderly patients (age ≥ 80 years) is limited.
Takumi Tamura, Yoshihisa Naruse, Taro Narumi, Yuki Tokonami, Yasukazu Takazawa, Kazuki Ito, Yutaro Kaneko, Makoto Sano, Ryosuke Takeuchi, Natsuko Hosoya, Masahiro Muto, Ryuta Henmi, Ryo Sugiura, Keisuke Miyajima, Yuichiro Maekawa   +14 more
doaj   +1 more source

Circulating mitochondrial cell-free DNA levels are associated with the recurrence of atrial fibrillation after catheter ablation for atrial fibrillation

American Heart Journal Plus
Background: Although catheter ablation, including pulmonary vein isolation, is the primary nonpharmacological therapy for atrial fibrillation (AF), atrial arrhythmia often recurs.
Tomoko Takahashi, Takeshi Soeki, Kazuki Tezuka, Tomomi Matsuura, Etsuko Uematsu, Hiroyuki Aibara, Ryou Bando, Robert Zheng, Tomonori Takahashi, Yoshihito Saijo, Yutaka Kawabata, Muneyuki Kadota, Tomoya Hara, Rie Ueno, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Hirotsugu Yamada, Daiju Fukuda, Masataka Sata   +19 more
doaj   +1 more source

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

Advanced Science, EarlyView.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su, Yi Li, Meng Xiao, Dan Guo, David S. Perlin, Erika Shor, Yingchun Xu, Yingxing Li   +7 more
wiley   +1 more source

Chronic obstructive pulmonary disease is associated with higher recurrence rates of atrial fibrillation following catheter ablation

Indian Pacing and Electrophysiology Journal
Background: Patients with atrial fibrillation (AF) and chronic obstructive pulmonary disease (COPD) are at increased risk of cardiovascular mortality compared to patients with AF alone.
Ree Lu, Devin Skoll, Ahmed Y. Gasmelseed, Geoffrey A. Rubin, Elaine Y. Wan, Amardeep S. Saluja, Jose M. Dizon, Angelo B. Biviano, Hasan Garan, Hirad Yarmohammadi   +9 more
doaj   +1 more source

Catheter Ablation [PDF]

Europace, 2011
A. Yaduvanshi, M. Kumar, V. Kataria, V. Arora, M. Nair, A. V. Ardashev, M. S. Rybachenko, E. G. Zhelyakov, A. V. Konev, D. Xv, B. Yang, M. Chen, F. Zhang, W. Ju, H. Chen, L. Zhai, J. Wang, J. Yu, Q. Shan, J. Zou, C. Chen, X. Hou, K. Cao, S. Termosesov, R. Garipov, I. Ilich, Y. Volkova, F. Zhang, M. Chen, B. Yang, H. Chen, W. Ju, D. Xu, J. Zou, Q. Shan, K. Cao, J. Liu, P.-h. Fang, Y. Hou, Y.-h. Jia, J.-m. Chu, Y. Yao, J. Ma, J.-l. Pu, S. Zhang   +44 more
openaire   +1 more source

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

Catheter Ablation

JACC: Clinical Electrophysiology, 2018
Peter M. Kistler, Aleksandr Voskoboinik
  +4 more sources

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

Advanced Science, EarlyView.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou, Qiong Xue, Su‐Xuan Hou, Ke‐Yao Zhang, Wei‐Tong Pan, Ting‐Ting Zeng, Yu‐Ge Wang, Daqing Ma, Chenguang Zhao, Pan‐Miao Liu, Jian‐Jun Yang   +10 more
wiley   +1 more source

A Dual‐Modal Wearable PPG Smartwatch with AI‐Enhanced Correction for High‐Accuracy and Continuous AF Burden Assessment

Advanced Science, EarlyView.
ABSTRACT Atrial fibrillation (AF) increases the risk of stroke and heart failure, yet accurate quantification of AF burden in daily life remains difficult. Although smartwatch photoplethysmography (PPG) supports continuous monitoring, complex rhythms and signal noise can impair burden estimation.
Song Zuo, Jinglei Wang, Xin Wang, Han Feng, Yize Zhao, Fadong Li, Shaobin Wei, Le Zhou, Zixu Zhao, Songjie Chen, Xiangyi Kong, Jue Wang, Liu He, Shijun Xia, Xin Li, Junmeng Zhang, Xiaoxia Liu, Xueyuan Guo, Ning Zhou, Songnan Li, Chenxi Jiang, Ribo Tang, Caihua Sang, Deyong Long, Xin Du, Jianzeng Dong, Wenwu Zhu, Changsheng Ma   +27 more
wiley   +1 more source