Results 81 to 90 of about 144,766 (342)

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Comparison of Ultrasound-Guided Vs Traditional Arterial Cannulation by Emergency Medicine Residents [PDF]

, 2020
Introduction: We sought to determine whether ultrasound-guided arterial cannulation (USGAC) is more successful than traditional radial artery cannulation (AC) as performed by emergency medicine (EM) residents with standard ultrasound training.Methods: We
Billioux, Veena, Bright, Leah, Kelen, Gabor D., Rose, David, Wilson, Casey   +4 more
core  

ESC core curriculum for the general cardiologist (2013) [PDF]

, 2013
[No abstract ...
A. Kitsiou, A. L. P. Caforio, A. Porta-Sanchez, A. Vahanian, B. Iung, C. Carrera, C. Szymanski, D. Herpin, D. Taggart, F. Calvo, F. Flachskampf, G. Ertl, G. Iaccarino, H. Burri, I. J. Nunez, J. Bauersachs, J. Bax, J. Hall, J. J. Monsuez, J. Lopez-Sendon, J. P. Schmid, J. R. Gonzalez-Juanatey, J. Stepinska, K. Zeppenfeld, L. Goncalves, L. Joubert, L. M. Ruilope, L. Tokgozoglu, M. J. Salvador, M. Sousa-Ouva, M. Tendera, N. Brooks, null null, null null, null null, null null, null null, null null, null null, O. A. Smiseth, P. A. Sirnes, P. Charron, P. Giannuzzi, P. Gueret, P. Kearney, P. Lancellotti, P. Trindade, R. B. A. van den Brink, R. Fontes-Carvalho, R. Griebenow, S. Gibbs, S. Plein, S. Price, S. Priori, T. C. Gillebert, T. McDonough, V. Regitz-Zagrosek, Z. Fras, Z. Reiner   +58 more
core   +2 more sources

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

Research progress on the application of PICC in patients with permanent cardiac pacemaker implantation

Huli yanjiu, 2023
This paper reviewed research status quo of peripherally inserted central venous catheters（PICC） in patients with permanent cardiac pacemaker implantation，including multidisciplinary team assessment before PICC catheterization，selection of PICC ...
LIU Chunli, YAN Meiqiong, XUE Hui, LI Xiaoxu, LIU Lagen, SHI Ruchun, MENG Aifeng, ZHAO Yun, ZHANG Liuliu   +8 more
doaj  

An unusual complication of central venous catheterization

CHRISMED Journal of Health and Research, 2015
An 87-year-old female, a known case of diabetes mellitus was admitted with acute febrile illness with altered sensorium and uncontrolled hyperglycemia. She was evaluated and diagnosed to have urosepsis, septic shock and lactic acidosis.
Vignesh Kumar Chandiraseharan, A R Malathy   +1 more
doaj   +1 more source

A Sirtuin‐1‐Targeted Gene‐Activating Tetrahedral DNA Attenuates Bladder Fibrosis by Restoring Mitophagy in Fibroblasts via the SIRT1‐FOXO3‐BNIP3 Axis

Advanced Science, EarlyView.
The SIRT1‐targeted saRNA‐delivering tetrahedral DNA (TSA) treatment effectively upregulates SIRT1 expression, which subsequently promotes FOXO3A deacetylation. This deacetylation event relieves FOXO3A's transcriptional repression on the BNIP3 gene, thereby initiating PINK1‐PARKIN‐dependent mitophagy.
Wei Wang, Ran Yan, Lede Lin, Lei Xiang, Xiaozhi Xia, Liao Peng, Xiaoshuai Gao, Jiawei Chen, Yang Xiong, Liang Zhou, Yunfeng Lin   +10 more
wiley   +1 more source

COMPARISON OF INTERNAL JUGULAR VEIN WITH SUBCLAVIAN VEIN HEMODIALYSIS CATHETER ACCESS

Journal of University Medical & Dental College, 2017
Objectives: To compare internal jugular vs. subclavian venous approach for the placement of central venous line for hemodialysis in term of complication. Material and methods: All Patients requiring placement of central venous catheter for dialysis, were
Muhammad Khalid, Muhammad Akram Malik, Muhammad Imran bhatti et al.   +2 more
doaj  

Improving Proficiency in Central Venous Catheter Insertion: Standardized Simulation Based Training for Internal Medicine House Staff [PDF]

, 2017
Objectives: The objectives of this study are to assess residents\u27 pre-workshop ability and comfort with CVC placement, undergo a standardized online didactic and hands-on clinical training simulation workshop, and subsequently undergo a proficiency ...
Hutchinson, MD, MA, Christoph, Madara, MD, John, West, MD, MS, Frances Mae   +2 more
core   +1 more source

Intelligent Soft Opto‐Magnetic Robot for Minimally Invasive Interventional Therapy

Advanced Science, EarlyView.
An intelligent soft opto‐magnetic (iSOM) robot is developed that integrates remote magnetic actuation, skin‐mimic tactile perception, and photothermal ablation in a near‐millimeter‐scale design. It enables precise intraluminal navigation and localized ablation while providing real‐time optical feedback to support safe and accurate minimally invasive ...
Jingjing Guo, Xiaoyan Guo, Jian Wei, Miaowen Jiang, Qifa Su, Xian Xia, Zhuozhou Li, Rong Cai, Jianguo Ma, Bo Fu, Ming Li, Jing Zhong, Lijun Xu, Xunming Ji   +13 more
wiley   +1 more source