Results 181 to 190 of about 717,783 (259)

Mesenchymal stem cells as cellular factories for targeted P2X7 blockade after traumatic brain injury

Neuroprotection, EarlyView.
This manuscript presents a novel therapeutic strategy using mesenchymal stem cells (MSCs) engineered as living drug factories to deliver a P2X7‐blocking nanobody for treatment of ischemic stroke. By combining targeted cellular delivery with sustained local immunomodulation, the approach aims to overcome key limitations of systemic biologic ...
Lucia Fadon‐Padilla, Chengyan Chu, Lorissa McDougall, Yajie Liang, Chinmoy Sarkar, Marta Lipinski, Tim Magnus, Miroslaw Janowski, Piotr Walczak   +8 more
wiley   +1 more source

Analysis of portal vein thrombosis prevalence and risk factors in neonates following umbilical venous catheterization: a systematic review and meta-analysis. [PDF]

J Pediatr (Rio J)
Novaes RM, de Alcântara RV, Hessel G.
europepmc   +1 more source

Perspectives in Pediatric Ambulatory Anesthesia: Part 3—One Center's Evolving Regional Anesthesia Experience and Outcomes

Pediatric Anesthesia, EarlyView.
ABSTRACT Introduction Pediatric ambulatory surgery is the dominant model of surgical care in the U.S. and has impacted the practice of regional anesthesia (RA). Pediatric RA's use has expanded as a supplement to general anesthesia with the introduction of ultrasound.
David E. Liston, Elizabeth E. Hansen, Jennifer L. Chiem, Sean H. Flack, Daniel K. W. Low, Lynn D. Martin   +5 more
wiley   +1 more source

On-Table Versus Deferred Extubation After Paediatric Cardiac Catheterisation Under General Anaesthesia: A Retrospective Cohort Study. [PDF]

J Cardiovasc Dev Dis
Gürsoy Çirkinoğlu G, Şahinkaya HH, Salman Önemli C, Efe MA, Gürlek M, Kaykaç M, Bulut MO, Gerçeker E.   +7 more
europepmc   +1 more source

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

Glutathione Redox Changes in Pulmonary Arterial Blood After Remote Ischemic Conditioning in Pulmonary Hypertension: A Single-Arm Pilot Study. [PDF]

Antioxidants (Basel)
Yang S, Li L, Zhang J, Qiao X, Sun W, Zhao W, Hu H, Xi Q, Li Y, Guo X, Wang J, Gong J, Yang Y, Chen C, Ji X, Zhang X, Yang Q.   +16 more
europepmc   +1 more source

Evaluating the efficacy of obturator cryoneurolysis for hip adductor spasticity: An observational, prospective study

PM&R, EarlyView.
Abstract Background Hip adductor spasticity is a common affliction among patients with disorders of the central nervous system. Cryoneurolysis is a novel intervention for spasticity involving the application of extreme cold to a nerve. This induces axonal breakdown, relieving spasticity.
Fraser MacRae, Mahdis Hashemi, Paul Winston   +2 more
wiley   +1 more source

Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Right Heart Catheterization in a Patient With Breast Cancer: A Case Report. [PDF]

Cureus
Tajima S, Nakata Y, Sanda K, Koshimo Y, Shigematsu M.   +4 more
europepmc   +1 more source

Preclinical Efficacy and Safety Evaluation of a Novel Controlled‐Expansion ePTFE‐Covered TIPS Stent in a Swine Model

Portal Hypertension &Cirrhosis, EarlyView.
This preclinical study evaluated a novel controlled‐expansion expanded polytetrafluoroethylene (ePTFE)‐covered transjugular intrahepatic portosystemic shunt (TIPS) stent in 11 swine, demonstrating 100% technical success, excellent deployability, and durable 6‐month angiographic patency without thrombosis, migration, fracture, or device‐related toxicity.
Yi Xiang, Qi Zhang, Chuan Liu, Jiawei Zhang, Qingqiao Zhang, Changsheng Shi, Chunze Zhou, Yudong Zhang, Hongliang He, Hao Xie, Hui Shi, Haijian Guo, Wenjing Liu, Muqing Lin, Huajie Yu, Xiaolong Qi   +15 more
wiley   +1 more source

Oxygen utilization during moderate-intensity resistance and aerobic exercise in arrhythmogenic cardiomyopathy: the central role of the periphery. [PDF]

ESC Heart Fail
Wernhart S, Rattka M, Shir M, Laugwitz KL, Halle M, Haykowsky MJ.   +5 more
europepmc   +1 more source