Results 151 to 160 of about 26,086 (270)

Pharmacokinetic Evaluation of a Cinnamon Product on CYP2A6 Substrate Drugs: Application of a Novel Tool Involving the Nicotine Metabolite Ratio

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1485-1493, June 2026.
Cinnamon (Cinnamomum spp.) is used as a culinary spice and dietary supplement. A major constituent, cinnamaldehyde, was previously shown to inactivate cytochrome P450 (CYP) 2A6 in vitro. A mechanistic static model predicted an ~5‐fold increase in the AUC of the CYP2A6 substrates nicotine and letrozole.
Aiden‐Hung P. Nguyen   +8 more
wiley   +1 more source

Harnessing Fatty Acid By‐Products for Diabetes Management: Insights From Nutritional and Biological Research

open access: yeseFood, Volume 7, Issue 3, June 2026.
Bioactive fatty acids from agro‐industrial byproducts are highlighted as a promising avenue for managing diabetes in this review, which aims to develop targeted interventions for optimal utilization and therapeutic benefits. ABSTRACT Diabetes mellitus (DM), influenced by multifaceted factors, creates a complex imbalance within the body. Nutrition plays
Youssef Elouafy   +7 more
wiley   +1 more source

Retrospective Evaluation of Dual Specialty Ports in Therapeutic Apheresis

open access: yesJournal of Clinical Apheresis, Volume 41, Issue 3, June 2026.
ABSTRACT Dual specialty ports were evaluated for safety and efficacy in therapeutic apheresis by analyzing outcomes across 97 port placement events in 88 patients, focusing on two configurations: dual Bard PowerFlow (BP2) and a combination of Bard PowerFlow with AngioDynamics SmartPort (BP + AD).
Mugtaba Swar‐Eldahab   +3 more
wiley   +1 more source

Fungal‐Bacterial Interactions in Polymicrobial Infections: Hidden Threats

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
ABSTRACT Polymicrobial infections involving fungi and bacteria represent a major and increasingly recognized clinical challenge, in which interkingdom interactions significantly amplify disease severity, antimicrobial resistance, and treatment failure. Rather than passive co‐existence, fungal–bacterial communities form highly coordinated systems driven
Mohammad Javad Roustaye Gourabi   +3 more
wiley   +1 more source

Interplay Between Virulence Genes, Antimicrobial Resistance Profiles, and Biofilm Formation in Klebsiella pneumoniae Causing Urinary Tract Infections in North Lebanon

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
– Figure design (single panel) Central icon: K. pneumoniae cell Left panel – Virulence genes (icons): Adhesion: fimH, mrkD → strong biofilm Capsule/regulation: magA, rmpA Siderophores: entB, iucA → iron uptake Right panel – Outcomes: Biofilm strength (weak → strong gradient) Antibiotic resistance (ESBL, MDR) Bottom split: Hospital‐acquired → strong ...
Mazen Zaylaa   +8 more
wiley   +1 more source

A case of yogurt central line‐associated bloodstream infection in a child with intestinal failure

open access: yesNutrition in Clinical Practice, Volume 41, Issue 3, Page 968-973, June 2026.
Abstract Central line‐associated bloodstream infections (CLABSI) are a significant cause of morbidity in children with intestinal failure (IF). Probiotic therapy is discouraged in patients with IF because of the increased risk of bacteremia with the probiotic organism.
Nasiha Rahim   +6 more
wiley   +1 more source

Application of problem‐oriented model combined with situational simulation teaching method in the training of intravenous infusion skills for pediatric rotation nurses

open access: yesPrecision Medical Sciences, Volume 15, Issue 2, Page 123-127, June 2026.
This paper explores the application of the problem‐oriented model based on the joint situational simulation teaching method in the training of intravenous infusion skills of pediatric nurses on rotation. The scores of the experimental group on the theoretical exam, the scenario simulation exam, and the practical exam were all significantly higher than ...
Lin Zhang   +7 more
wiley   +1 more source

Advances in Erectile Dysfunction Management: What Does Work

open access: yesTrends in Urology &Men's Health, Volume 17, Issue 3, June 2026.
ABSTRACT Erectile dysfunction (ED) is a prevalent and multifactorial disorder that substantially affects quality of life. Pathophysiology includes vascular, neurogenic, drug‐induced, and psychogenic causes, and frequently coexists with cardiometabolic disease.
Jolie Shen   +3 more
wiley   +1 more source

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