Results 21 to 30 of about 266 (95)
Leukocyte count and new‐onset diabetes mellitus in people with HIV: A longitudinal study
HIV Medicine, Volume 26, Issue 10, Page 1585-1599, October 2025.Abstract Objectives
The risk of diabetes mellitus (DM) is increased in people with HIV. Chronic inflammation contributes to DM risk. High leukocytes are associated with DM in the general population, but in people with HIV, evidence of a leukocyte–DM association is limited. Methods
We included participants of the Swiss HIV Cohort Study with new‐onset DM Sophia C. Meyer, Zoe Klein, Isabella C. Schoepf, Christian W. Thorball, Marco Labarile, Neeltje A. Kootstra, Peter Reiss, Lene Ryom, Dominique L. Braun, Maria C. Thurnheer, Catia Marzolini, Christian R. Kahlert, Enos Bernasconi, Matthias Cavassini, Annalisa Marinosci, Jacques Fellay, Huldrych F. Günthard, Roger D. Kouyos, Bruno Ledergerber, Philip E. Tarr, the Swiss HIV Cohort Study, I Abela, K Aebi‐Popp, A Anagnostopoulos, M Battegay, E Bernasconi, DL Braun, HC Bucher, A Calmy, M Cavassini, A Ciuffi, G Dollenmaier, M Egger, L Elzi, J Fehr, J Fellay, H Furrer, CA Fux, HF Günthard, A Hachfeld, D Haerry, B Hasse, HH Hirsch, M Hoffmann, I Hösli, M Huber, D Jackson‐Perry, patient representatives, CR Kahlert, O Keiser, T Klimkait, RD Kouyos, H Kovari, K Kusejko, N Labhardt, K Leuzinger, B Martinez de Tejada, C Marzolini, KJ Metzner, N Müller, J Nemeth, D Nicca, J Notter, P Paioni, G Pantaleo, M Perreau, A Rauch, L Salazar‐Vizcaya, P Schmid, R Speck, M Stöckle, P Tarr, A Trkola, G Wandeler, M Weisser, S. Yerly +75 morewiley +1 more sourceThe Introduction of Extended Out‐of‐Home Care (OOHC) Until 21 Years in Australia: A Mapping of Policy, Legislation and Programs in Each Jurisdiction
Australian Journal of Social Issues, Volume 60, Issue 3, Page 689-700, September 2025.ABSTRACT
It is increasingly recognised by global research that extending out‐of‐home care (OOHC) until at least 21 years of age is the policy reform most likely to advance improved outcomes for care leavers. In recent years, all eight Australian jurisdictions (States and Territories) have introduced forms of extended care programs.Philip Mendes, Steven Roche, Isabella Kristo, Melissa O'Donnell, Tim Moore, Catia Malvaso, Jemma Venables, Joseph McDowall +7 morewiley +1 more sourceTime Perspective Matters for Working Alliance in Schizophrenia Care: Insights From the DiAPAson Project
Clinical Psychology &Psychotherapy, Volume 32, Issue 5, September/October 2025.ABSTRACT Objectives
The time perspective dimensions and balanced time perspective (BTP) may play a crucial role in the therapeutic process of individuals with schizophrenia spectrum disorders (SSDs). This study aimed to investigate the relationship between BTP, working alliance (WA) and psychiatric symptomatology in individuals with SSD.Cristina Zarbo, Maciej Stolarski, Donato Martella, Elena Toffol, Giovanni de Girolamo, for the DIAPASON consortium +5 morewiley +1 more sourceThe Juvenile Parkinson's Disease Mutation C212Y Impairs Mitochondrial Homeostasis in a Caenorhabditis elegans Model
The FASEB Journal, Volume 39, Issue 16, 31 August 2025.Only a small subset of the Parkin missense mutations have been studied. Considering the high conservation of the protein, we examined the feasibility of generating a PD disease missense mutation in C. elegans using the Crispr/Cas9 technology. Shown here is the PDR‐1C169Y allele, the equivalent mutation of Parkin C212Y identified in autosomal recessive ...Eyal Spector, Lirin Michaeli, Anat Nitzan, Hanna Grobe, Gabriel Axel, Ulrike Bening Abu‐Shach, Hen Zinger, Cátia A. Carvalho, Ronen Zaidel‐Bar, Limor Broday +9 morewiley +1 more sourceSGLT2 inhibitor with and without ALDosterone AntagonIst for heart failure with preserved ejection fraction: Design paper
ESC Heart Failure, Volume 12, Issue 4, Page 3134-3144, August 2025.Abstract Background
Sodium glucose co‐transporter 2 inhibitors (SGLT2i) and mineralocorticoid receptor antagonists (MRA) reduce heart failure (HF) events in patients with heart failure and mildly reduced or preserved ejection fraction (HFmr/pEF). The randomized comparison of SGLT2i/MRA combination versus SGLT2i or MRA alone requires further testing in ...João Pedro Ferreira, Francisco Vasques‐Nóvoa, Francisca Saraiva, Ana C. Oliveira, Jorge Almeida, Ana Beatriz Batista, Arsénio Barbosa, Ana Filipa Ferreira, Cátia Costa, Diogo Santos‐Ferreira, Fernando Friões, Cândida Goncalves, João Tiago Guimarães, Marta Leite, Pedro Marques, Joana Mascarenhas, Maria Inês Matos, Catarina Pereira, Pedro Rodrigues, Abhinav Sharma, Gualter Silva, Inês Pereira‐Sousa, Carla Sousa, Faiez Zannad, Joana Pimenta, Ricardo Fontes‐Carvalho, Adelino Leite‐Moreira +26 morewiley +1 more sourceCDK13‐Related Disorder: Novel Insights From A Series of 27 Cases and Recommendations for Clinical Management
Clinical Genetics, Volume 108, Issue 2, Page 146-155, August 2025.This report described 27 novel subject with CDK13‐related disorders. Collecting the clinical and radiological data, we better define the phenotypic spectrum of this condition and we suggest a comprehensive clinical management. ABSTRACT
In 2016, Sifrim and colleagues described the first group of patients carrying heterozygous pathogenic variants in ...Gianluca Contrò, Maria Chiara Baroni, Stefano Giuseppe Caraffi, Manuela Napoli, Rosangela Artuso, Annarita Giliberti, Sara Bargiacchi, Giorgia Mancano, Giovanna Traficante, Mafalda Mucciolo, Francesca Clementina Radio, Viviana Cordeddu, Cecilia Mancini, Irene Bottillo, Federica Anna Pirro, Maria Teresa Bonati, Cord‐Christian Becker, Diana Carli, Alessandro Mussa, Maria Isis Atallah Gonzalez, Inge Lore Ruiz‐Arana, Camille Kumps, Isabelle Maystadt, Stephanie Moortgat, Alp Peker, Maria Piccione, Paola Grammatico, Nino Rostomashvili, Jonathan Lévy, Marcello Scala, Valeria Capra, Annalaura Torella, Clare van Eyk, Bertrand Isidor, Benjamin Cogne, Siddharth Srivastava, Aisling Quinlan, Alessandro Vaisfeld, Laura Licchetta, Daniele Frattini, Claudio Graziano, Giulia Severi, Isabelle Bacchi, Luca Soliani, Elliott H. Sherr, Emanuela Argilli, Himanshu Goel, Chiara De Luca, Silvia Leonardi, Francesco Brancati, Flavio Faletra, Catia Mio, Silvia Braibanti, Giancarlo Gargano, Carlo Fusco, Antonio Novelli, Marco Tartaglia, Livia Garavelli +57 morewiley +1 more sourceAdenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study
FEBS Open Bio, Volume 15, Issue 7, Page 1159-1175, July 2025.The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori +15 morewiley +1 more sourceEffects of GBA1 Variants in Patients With Parkinson's Disease and Levodopa–Carbidopa Intestinal Gel: A Nation‐Wide, Multicenter, Longitudinal, “Real‐World” Study. The EPIC Study
European Journal of Neurology, Volume 32, Issue 7, July 2025.ABSTRACT Background
The outcome of levodopa/carbidopa intestinal gel (LCIG) in Parkinson's disease carriers of GBA1 mutations (GBA‐PD) remains uncertain. Objective
To evaluate the safety and efficacy of LCIG in a large PD cohort, focusing on GBA1 variants.Roberto Cilia, Fabiana Colucci, Emanuele Cereda, Antonio E. Elia, Valentina Leta, Silvia Barca, Maurizio Zibetti, Miryam Carecchio, Salvatore Bonvegna, Giovanna Calandra‐Buonaura, Rocco Cerroni, Rosa De Micco, Stefano Tamburin, Luca Magistrelli, Francesco Lena, Marcello M. Mascia, Marina Picillo, Giovanni Cossu, Massimo Marano, Alessandro Zampogna, Clelia Pellicano, Valentina Fioravanti, Andrea Pilotto, Roberta Zangaglia, Micol Avenali, Chiara Sorbera, Francesca Di Biasio, Federica Arienti, Alessandra Nicoletti, Caterina Bagella, Maria Chiara Malaguti, Alessandra Ranghetti, Elena Caputo, Dario Alimonti, Elena Torre, Gaia D. Oggioni, Catia Leuzzi, Luigi M. Romito, Nico Golfrè Andreasi, Grazia Devigili, Roberta Telese, Arianna Braccia, Gianfranco Gaudiano, Samanta Mazzetti, Federica Invernizzi, Barbara Garavaglia, Gabriele Imbalzano, Claudia Ledda, Pietro Antenucci, Andrea Gozzi, Giulia Bonato, Marco Percetti, Giulia Giannini, Luisa Sambati, Tommaso Schirinzi, Martina D'Anna, Domiziana Rinaldi, Francesco Cavallieri, Marco Liccari, Alberto Priori, Maria Sessa, Filippo Tamma, Margherita Canesi, Paolo Solla, Mario Zappia, Alessio Di Fonzo, Laura Avanzino, Angelo Quartarone, Enza Maria Valente, Claudio Pacchetti, Alessandro Padovani, Franco Valzania, Francesco E. Pontieri, Antonio Suppa, Maria Teresa Pellecchia, Nicola Modugno, Cristoforo Comi, Michele Tinazzi, Alessandro Tessitore, Alessandro Stefani, Pietro Cortelli, Ioannis U. Isaias, Angelo Antonini, Mariachiara Sensi, Leonardo Lopiano, Roberto Eleopra +85 morewiley +1 more sourceCover Picture and Issue Information
Ecological Solutions and Evidence, Volume 7, Issue 1, January–March 2026.Cover image: View of an Opuntia echios var. echios cactus through a rusted metal tank, photographed on Baltra Island, Galápagos, Ecuador, during a monitoring expedition for the Galápagos Verde 2050 program of the Charles Darwin Foundation. Taken in May 2020.wiley +1 more sourceReply to Elias et al.: Multiproxy evidence of widespread landscape disturbance in multiple Azorean lakes before the Portuguese arrival. [PDF]
Proc Natl Acad Sci U S A, 2022 Raposeiro PM, Hernández A, Pla-Rabes S, Gonçalves V, Bao R, Sáez A, Shanahan T, Benavente M, de Boer EJ, Richter N, Gordon V, Marques H, Sousa PM, Souto M, Matias MG, Aguiar N, Pereira C, Ritter C, Rubio MJ, Salcedo M, Vázquez-Loureiro D, Margalef O, Amaral-Zettler LA, Costa AC, Huang Y, van Leeuwen JFN, Masqué P, Prego R, Ruiz-Fernández AC, Sanchez-Cabeza JA, Trigo R, Giralt S. +31 moreeuropepmc +1 more source
