Influence of Dystrophin Isoform Deficiency on Motor Development in Duchenne Muscular Dystrophy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In Duchenne muscular dystrophy (DMD), lack of the shorter dystrophin isoforms Dp140 and Dp71 is associated with increased central nervous system (CNS) involvement. We aimed to investigate how CNS involvement affects motor development in young DMD boys.
Mary Chesshyre +152 more
wiley +1 more source
DIFFERENCES BETWEEN EXPERIMENTAL RIGIDITIES IN CATS [PDF]
, 1938 E. G. T. Liddell
openalex +1 more source
Understanding Mechanisms of Whole Brain and Regional Grey Matter Atrophy in Children With MOGAD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To investigate the mechanisms driving whole brain and regional grey matter (GM) volume changes along with their clinical correlates in paediatric myelin oligodendrocyte glycoprotein antibody (MOG‐Ab)–associated disease (MOGAD). Methods One‐hundred‐nine paediatric MOGAD patients from two UK centres underwent MRI at attack nadir and ...
Ermelinda De Meo +14 more
wiley +1 more source
Vaccination Status of Horses in Poland Based on an Internet Survey of the Horse Owners
AnimalsPreventing the spread of infectious diseases in horses requires breaking the chain of infection through appropriate prophylaxis. In Poland, where the horse population reached 273,006 in 2023, vaccinations are voluntary and primarily the responsibility of
Marta Rykala +2 more
doaj +1 more source
THE RELEASE OF ADRENALINE AND NORADRENALINE FROM THE ADRENAL MEDULLA OF THE CAT DURING SPLANCHNIC STIMULATION [PDF]
, 1958 Nicholas Bade, D. R. Wood
openalex +1 more source
In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock +8 more
wiley +1 more source
Journal of Veterinary Internal MedicineBackground Brain imaging suggests the involvement of the limbic system, particularly the cingulate gyrus (GC), in dogs with idiopathic epilepsy (IE). Hypothesis A correlation exists between the side of interictal epileptiform discharges (IEDs) and the ...
Aleksandra Banasik +6 more
doaj +1 more source
Discovery and Treatment of Action Potential‐Independent Myotonia in Hyperkalemic Periodic Paralysis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hyperkalemic periodic paralysis (hyperKPP) is characterized by attacks of transient weakness. A subset of hyperKPP patients suffers from transient involuntary contraction of muscle (myotonia). The goal of this study was to determine mechanisms causing myotonia in hyperKPP.
Chris Dupont +4 more
wiley +1 more source
Evaluating skip-stop policy in urban rail transit systems based on passenger cost
Journal of Public Transportation, 2023 Increasing the operating speed in public transport systems can increase the system capacity, reduce the overall passenger travel time and improve experienced comfort.
Soumela Peftitsi +2 more
doaj
LIN28B Promotes Cancer Cell Dissemination and Angiogenesis
Advanced Biology, EarlyView.Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo +8 more
wiley +1 more source