Results 41 to 50 of about 601,018 (313)

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Disposal rate in different age groups of Karan Fries (Crossbred) males in organized herd [PDF]

Veterinary World, 2015
Aim: The present study was carried out to analyze the disposal rate in different age groups of Karan Fries (KF) males in National Dairy Research Institute herd.
Achun Panmei, A. K. Gupta, P. R. Shivahre, M. Bhakat , K. Mahesh Singh   +4 more
doaj   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

QUALITY INDICATORS OF BEEF FROM YOUNG BULLS OF VARIOUS DAIRY AND BEEF BREEDS

Теория и практика переработки мяса, 2017
It was established that studied meat raw material from young bulls of different breeds (Group I — red steppe, Group II — black-andwhite, Group III — Kalmyk, 15 animals per group) was balanced by amino acid and fatty acid composition and by fatty acid ...
S. A. Miroshhikov, A. V. Kharlamov, I. V. Markova   +2 more
doaj   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Optimal Incentive Structure in Cattle Feeding Contracts Under Alternative Fed Cattle Pricing Methods [PDF]

Developing a multitask principal-agent model, this paper theoretically analyzes the incentive provisions in the existing cattle feeding contracts under alternative fed cattle pricing methods.
Rahman, Shaikh Mahfuzur
core   +2 more sources

Understanding Sport Participation and Athlete Development: The Exposure to Sport Scale

Current Issues in Sport Science
The purpose of this two-part paper was to conceptualize and validate a new method for measuring youth sport exposure. In part one, different disciplines were used to guide the creation of the Exposure to Sport Scale.
Alexandra Mosher, Antonia Cattle, Jessica Fraser-Thomas, Joseph Baker   +3 more
doaj   +1 more source

Estimation of genetic parameters of weekly test-day milk yields and first lactation 305-day milk yield in Murrah buffaloes [PDF]

Veterinary World, 2014
Aim: The aim was to estimate genetic parameters of weekly test-day (TD) milk yields and first lactation 305-day milk yield (FL305DY) in Murrah buffaloes.
Saroj Kumar Sahoo, Avtar Singh, A. K. Gupta, A. K. Chakravarty, Manvendra Singh , G. S. Ambhore   +5 more
doaj   +1 more source

Tri‐Functional Electrocatalysis for Zinc–Air Battery Coupled Water Splitting: A Catalyst‐Electrode‐Device‐System Perspective

Advanced Science, EarlyView.
This review establishes a catalyst–electrode–device–system framework for tri‐functional HER/OER/ORR electrocatalysis that couples water splitting with Zn–air batteries. Five catalyst families are covered: noble‐metal, metal‐based, single‐atom, heterostructure, and metal‐free systems.
Xixi Di, Chao Duan, Shuzhen Li, Yiyang Che, Xiaoshuang Liu, Chuanyin Xiong, Mengxia Shen, Yichao Wang, Derek Hao, Yonghao Ni   +9 more
wiley   +1 more source