Results 231 to 240 of about 543,048 (284)

Comparing deep learning CNN method with traditional MRI-based hippocampal segmentation and volumetry for early Alzheimer's disease diagnosis across diverse populations. [PDF]

Sci Rep
Ibrahim NSN, Suppiah S, Ibrahim B, Mohad Azmi NH, Seriramulu VP, Mohamad M, Hanafi M, Mohammad Sallehuddin H, Omar Sharif NN, Razali RM, Harrun NH.   +10 more
europepmc   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Simulated intra-individual skin color changes and their impact on facial attractiveness across Japanese, Chinese, and Caucasian faces. [PDF]

Front Psychol
Koizumi K, Nagashima M, Hirao N, Ohira H.   +3 more
europepmc   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim, Han Gil Seo, Roh‐Eul Yoo, Byung‐Mo Oh   +3 more
wiley   +1 more source

The role of genetic polymorphisms on drug response in Alzheimer's disease: a systematic review. [PDF]

BMC Med Genomics
Climacosa FMM, Ornos EDB, Gapaz NCLL, Guantia MGR, Cruz JMC, Manalo RVM, Yu ML, Qureshi AP, Carampel AC, Asis JLB, Reyes JCB, Dacasin AB, Anlacan VMM.   +12 more
europepmc   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Reimagining Early-Phase Clinical Development in Japan: From Regulatory Obligation to Global Acceleration. [PDF]

Clin Transl Sci
Kawakita Y, Matsumoto K, Hirano M, Inoue S, Mashita O, Tawara H, Sato M.   +6 more
europepmc   +1 more source

Sex Hormones Associate With Amyotrophic Lateral Sclerosis Risk and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) risk differs by sex and age, implicating sex hormones as potential modifiers. This study examined plasma levels of biologically active sex hormones and their association with ALS odds and survival in cases (females n = 131, males n = 189) and controls (females n = 138, males n = 150) from the University of ...
Stephen A. Goutman, David G. Stouffer, Dae‐Gyu Jang, Jihyun Park, Benjamin J. Murdock, Richard J. Auchus   +5 more
wiley   +1 more source

Reference Values for Permanent-Tooth Emergence in Hungarian Children: A Cross-Sectional Study. [PDF]

Dent J (Basel)
Kapusi-Papp Z, Máth J, Nemes JÁ.
europepmc   +1 more source