Results 91 to 100 of about 550,647 (331)

Caudate Volumes in Childhood Predict Severity of Tourette Syndrome in Early Adulthood

open access: yesPediatric Neurology Briefs, 2005
Basal ganglia volumes of 43 children with Tourette syndrome (TS) were measured on MRI before age 14 years, and clinical assessment conducted after age 16, an average of 7.5 years later, at Yale University, New Haven, CT, and Columbia University. New York.
J Gordon Millichap
doaj   +1 more source

Neural responses to facial and vocal expressions of fear and disgust [PDF]

open access: yes, 1998
Neuropsychological studies report more impaired responses to facial expressions of fear than disgust in people with amygdala lesions, and vice versa in people with Huntington's disease.
A. J. Calder   +11 more
core   +2 more sources

A 2‐Part, Open‐Label, Phase 1 Bioequivalence and Food‐Effect Study of Ubrogepant in Healthy Adult Participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract This Phase 1 study of ubrogepant was conducted to establish the bioequivalence (BE) of the 50‐ and 100‐mg to‐be‐marketed (TBM) tablet formulations with the clinical trial (CT) 100‐mg tablet formulation and evaluate the food effect on the bioavailability of the 100‐mg TBM tablet. This 2‐part study enrolled healthy participants aged 18‐45 years.
Ramesh Boinpally, Joel M. Trugman
wiley   +1 more source

Entrained neuronal activity to periodic visual stimuli in the primate striatum compared with the cerebellum

open access: yeseLife, 2019
Rhythmic events recruit neuronal activity in the basal ganglia and cerebellum, but their roles remain elusive. In monkeys attempting to detect a single omission of isochronous visual stimulus, we found that neurons in the caudate nucleus showed increased
Masashi Kameda   +2 more
doaj   +1 more source

Association Between Duration of Dysphagia Recovery and Lesion Location on Magnetic Resonance Imaging in Patients With Middle Cerebral Artery Infarction [PDF]

open access: yesAnnals of Rehabilitation Medicine, 2019
Objective To investigate association between lesion location on magnetic resonance imaging (MRI) performed after an infarction and the duration of dysphagia in middle cerebral artery (MCA) infarction.
Jae Ho Kim   +5 more
doaj   +1 more source

Reduced caudate and nucleus accumbens response to rewards in unmedicated individuals with major depressive disorder.

open access: yesAmerican Journal of Psychiatry, 2009
OBJECTIVE Major depressive disorder is characterized by impaired reward processing, possibly due to dysfunction in the basal ganglia. However, few neuroimaging studies of depression have distinguished between anticipatory and consummatory phases of ...
D. Pizzagalli   +9 more
semanticscholar   +1 more source

Spike detection in the wild: Screening of suspected temporal lobe epilepsy cases using a tailored 2‐channel wearable EEG

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To clinically validate the contribution of a custom‐built EEG wearable device (waEEG) compared to a full 10–20 electrode array ambulatory EEG (aEEG) for screening epilepsy cases in patients with suspected temporal lobe epilepsy (TLE) but negative routine EEGs. Methods Patients (aged 16–91 years) with clinically suspected TLE who were
Daniel Filipe Borges   +4 more
wiley   +1 more source

GRN mutation in a patient with a behavioral variant of frontotemporal lobar degeneration (bvFTD)

open access: yesFolia Neuropathologica, 2017
The clinical spectrum of frontotemporal lobar degeneration (FTLD) is characterized by personality changes, language impairment, and executive function deficits.
Sylwia Walczysková   +5 more
doaj   +1 more source

Efficacy and tolerability of perampanel as add‐on therapy in Dravet syndrome: A prospective real‐world study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To investigate the efficacy and tolerability of perampanel (PER) on Dravet syndrome in China by a prospective real‐world study. Methods We prospectively enrolled children with Dravet syndrome from the neurology clinic of Shenzhen Children's Hospital from September 2020 to October 2021.
Han Wang   +9 more
wiley   +1 more source

Is there a neuroanatomical basis of the vulnerability to suicidal behavior?: a coordinate-based meta-analysis of structural and functional MRI studies [PDF]

open access: yes, 2014
Objective: We conducted meta-analyses of functional and structural neuroimaging studies comparing adolescent and adult individuals with a history of suicidal behavior and a psychiatric disorder to psychiatric controls in order to objectify changes in ...
Baeken, Chris   +4 more
core   +2 more sources

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