Results 101 to 110 of about 550,647 (331)

Investigating the role of SARM1 in central nervous system

Ibrain, EarlyView.
Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang, Yuhang Shi, Jinglei Tian, Liming Tang, Fang Cao   +4 more
wiley   +1 more source

Study on microstructure of corpus striatum in patients with idiopathic rapid eye movement sleep behavior disorder using magnetic resonance imaging

Chinese Journal of Contemporary Neurology and Neurosurgery, 2017
Objective To investigate the structure of corpus striatum and the integrity of white matter fiber in patients with Parkinson's disease (PD) and idiopathic rapid eye movement sleep behavior disorder (iRBD).
Ya-meng ZHANG, Hong-li WANG, Ying-ying BAI, Wen-jie HE, Yang YOU, Hong-ju ZHANG, Jie-wen ZHANG   +6 more
doaj  

Progress of non‐motor symptoms in early‐onset Parkinson's disease

Ibrain, EarlyView.
This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang, Aidi Luo, Shusheng Liao, Mei Liu, Jun Zhang, Zucai Xu   +5 more
wiley   +1 more source

Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the "dopamine receptor".

Proceedings of the National Academy of Sciences of the United States of America, 1972
An adenylate cyclase that is activated specifically by low concentrations of dopamine has been demonstrated in homogenates of caudate nucleus of rat brain.
J. Kebabian, G. Petzold, P. Greengard
semanticscholar   +1 more source

Differentiation of dementia with Lewy bodies from Alzheimer's disease using a dopaminergic presynaptic ligand [PDF]

, 2002
Background: Dementia with Lewy bodies (DLB) is one of the main differential diagnoses of Alzheimer's disease (AD). Key pathological features of patients with DLB are not only the presence of cerebral cortical neuronal loss, with Lewy bodies in surviving ...
Costa, DC, Gacinovic, S, Ince, P, Katona, CLE, Livingston, G, McKeith, IG, Shaw, K, Stevens, T, Walker, RWH, Walker, Z   +9 more
core   +2 more sources

Research progress on the use of the optical coherence tomography system for the diagnosis and treatment of central nervous system tumors

Ibrain, Volume 11, Issue 1, Page 3-18, Spring 2025.
With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li, Ziba Ayi, Gonggong Lu, Haibo Rao, Feilong Yang, Jing Li, Jiachen Sun, Junlin Lu, Xulin Hu, Si Zhang, Xuhui Hui   +10 more
wiley   +1 more source

Age and gender effects on striatal dopamine transporter density and cerebral perfusion in individuals with non-degenerative parkinsonism: a dual-phase 18F-FP-CIT PET study

EJNMMI Research
Background Dual-phase fluorine-18 labeled N-3-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl) nortropane (18F-FP-CIT) positron emission tomography (PET) scans could be used to support disorders like Parkinson’s disease (PD).
Ji-Young Kim, Seo Young Kang, Byung Seok Moon, Bom Sahn Kim, Jee Hyang Jeong, Hai-Jeon Yoon   +5 more
doaj   +1 more source

Finasteride Has Regionally Different Effects on Brain Oxidative Stress and Acetylcholinesterase Activity in Acute Thioacetamide-Induced Hepatic Encephalopathy in Rats. [PDF]

PLoS ONE, 2015
Finasteride (FIN) inhibits neurosteroid synthesis and potentially improves the course of hepatic encephalopathy (HE). This study aimed to investigate the effects of FIN on brain oxidative stress and acetylcholinesterase (AchE) activity in acute ...
Dušan Mladenović, Nataša Petronijević, Tihomir Stojković, Milica Velimirović, Gordana Jevtić, Dragan Hrnčić, Tatjana Radosavljević, Aleksandra Rašić-Marković, Nebojša Maksić, Dragan Djuric, Olivera Stanojlović   +10 more
doaj   +1 more source

Dopamine, But Not Serotonin, Regulates Reversal Learning in the Marmoset Caudate Nucleus

Journal of Neuroscience, 2011
Studies of visual discrimination reversal learning have revealed striking neurochemical dissociations at the level of the orbitofrontal cortex (OFC) with serotoninergic, but not dopaminergic, integrity being important for successful reversal learning ...
Hannah F. Clarke, Gemma Hill, T. Robbins, A. Roberts   +3 more
semanticscholar   +1 more source

Resting-State Functional Connectivity in Late-Life Depression: Higher Global Connectivity and More Long Distance Connections [PDF]

, 2013
Functional magnetic resonance imaging recordings in the resting-state (RS) from the human brain are characterized by spontaneous low-frequency fluctuations in the blood oxygenation level dependent signal that reveal functional connectivity (FC) via their
Blamire, Andrew, Bohr, Iwo Jerzy, Kaiser, Marcus, Kenny, Eva, O'Brien, John T., Richardson, Jonathan, Thomas, Alan J.   +6 more
core   +3 more sources