Results 211 to 220 of about 550,647 (331)

Development of Carbon‐11 Labeled Pyrimidine Derivatives as Novel Positron Emission Tomography (PET) Agents Enabling Brain Sigma‐1 Receptor Imaging

Advanced Science, Volume 12, Issue 21, June 5, 2025.
Novel carbon‐11 labeled pyrimidine derivatives are developed as PET imaging probes for visualizing sigma‐1 receptors in the brain. [11C]CNY‐01 demonstrates superior brain uptake and binding specificity in both rodents and non‐human primates. The study reveals decreased sigma‐1 receptor expression in Alzheimer's disease, offering a promising tool for ...
Ping Bai, Ashley Gomm, Chi‐Hyeon Yoo, Prasenjit Mondal, Fleur Marie Lobo, Hui Meng, Yanting Zhou, Weiyao Xie, Hsiao‐Ying Wey, Rudolph E. Tanzi, Can Zhang, Changning Wang, Yu Lan   +12 more
wiley   +1 more source

The Effect of Clozapine on Caudate Nucleus Volume in Schizophrenic Patients Previously Treated with Typical Antipsychotics [PDF]

, 2001
Floortje Scheepers
openalex   +1 more source

Three‐dimensional surface deformation‐based shape analysis of hippocampus and caudate nucleus in children with fetal alcohol spectrum disorders

Human Brain Mapping, 2014
J. Joseph, C. Warton, S. Jacobson, J. Jacobson, C. Molteno, A. Eicher, P. Marais, O. Phillips, K. Narr, E. Meintjes   +9 more
semanticscholar   +1 more source

Cell type-specific multi-omics analysis of cocaine use disorder in the human caudate nucleus. [PDF]

Nat Commun
Zillich L, Artioli A, Pohořalá V, Zillich E, Stertz L, Belschner H, Jabali A, Frank J, Streit F, Avetyan D, Völker MP, Müller S, Hansson AC, Meyer TD, Rietschel M, Ladewig J, Spanagel R, Oliveira AMM, Walss-Bass C, Bernardi RE, Koch P, Witt SH.   +21 more
europepmc   +1 more source

Differential functional dysconnectivity of caudate nucleus subdivisions in Parkinson's disease. [PDF]

Aging (Albany NY), 2020
Jia X, Pan Z, Chen H, Wang Z, Li K, Wang X, Wang Z, Ma H, Feng T, Yang Q.   +9 more
europepmc   +1 more source

Regional Cerebral Atrophy Contributes to Personalized Survival Prediction in Amyotrophic Lateral Sclerosis: A Multicentre, Machine Learning, Deformation‐Based Morphometry Study

Annals of Neurology, Volume 97, Issue 6, Page 1144-1157, June 2025.
Objective Accurate personalized survival prediction in amyotrophic lateral sclerosis is essential for effective patient care planning. This study investigates whether grey and white matter changes measured by magnetic resonance imaging can improve individual survival predictions.
Isabelle Lajoie, Canadian ALS Neuroimaging Consortium (CALSNIC), Sanjay Kalra, Christopher Hanstock, Alan Wilman, Dean Eurich, Christian Beaulieu, Yee Hong Yang, Lawrence Korngut, Richard Frayne, Hannah Briemberg, Lorne Zinman, Simon Graham, Angela Genge, Annie Dionne, Nicolas Dupré, Christen Shoesmith, Michael Benatar, Robert Welsh, Sanjay Kalra, Mahsa Dadar   +20 more
wiley   +1 more source

Effects of TRH and an Analog, DN-1417 on the Activities of Single Neurons in the Nucleus Accumbens, Cerebral Cortex and Caudate-putamen of Rats

, 1983
Tadatoshi Hashimoto, Naohisa Fukuda, Yoshiaki Saji, Yuji Nagawa   +3 more
openalex   +2 more sources

The subcortical anatomy of human spatial neglect: putamen, caudate nucleus and pulvinar [PDF]

, 2002
H.‐O. Karnath, Marc Himmelbach, Chris Rorden   +2 more
openalex   +1 more source

Relative sparing of dopaminergic terminals in the caudate nucleus is a feature of rest tremor in Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Mendonça MD, Ferreira PC, Oliveira F, Barbosa R, Meira B, Costa DC, Oliveira-Maia AJ, da Silva JA.   +7 more
europepmc   +1 more source

Differentiating Treatment‐Resistant Depression With and Without Parkinsonism in the Elderly From a Psychiatric Perspective by 99mTc‐TRODAT‐1 SPECT Imaging

International Journal of Geriatric Psychiatry, Volume 40, Issue 6, June 2025.
ABSTRACT Objectives Late‐life depression often overlaps with neurodegenerative diseases leading to diagnostic and treatment challenges for neuropsychiatrists. This study aimed to differentiate elderly treatment‐resistant depression (TRD) comorbid with parkinsonism from elderly TRD without Parkinsonism as well as elderly healthy controls using striatum ...
Tung‐Ping Su, Chiu‐Jung Huang, Wei‐Chung Mao, Yu‐Hsien Chiu, Ren‐Shyan Liu, Li‐Fen Chen   +5 more
wiley   +1 more source