Results 241 to 250 of about 53,163 (291)
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Effect of haloperidol on caudate nucleus
International Journal of Neuropharmacology, 1967Summary Dogs receiving haloperidol (7.5 mg/kg) orally showed a significant reduction in dopamine only in the caudate nucleus; the hypothalamus, hippocampus and pons being relatively unaffected. Behaviorally such animals showed tremors, especially of the head.
W A, Himwich, S N, Glisson
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Stimulation of Caudate Nucleus
Archives of Neurology, 1961Studies employing electrical stimulation in chronically prepared, freely moving animals have given disappointingly little information about the functions of the caudate nucleus. In those instances in which positive motor responses have been reported, 1,2,7 there is still the problem of refuting or confirming Kinnier Wilson's arguments that the effects ...
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Caudate Nucleus Lesions and Rearing Responses
Psychological Reports, 1975Lesioned rats were observed for 10-min. in a wooden enclosure. Frequencies of rearing were greatest for unoperated, frontal lesioned, and least for those with caudate lesions. Increased arousal of rats with caudate lesions was suspected.
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Dopamine receptors in canine caudate nucleus
Molecular and Cellular Biochemistry, 1982Physiological, pharmacological, histochemical and biochemical studies indicate that dopamine receptors are heterogenous in the central nervous system with each individual functions. This review describes pharmacological and biochemical characteristics of dopamine receptors, particularly in canine caudate nucleus, which have been studied in our ...
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Fatigability of caudate nucleus stimulation in cats
Neuropsychologia, 1976Abstract Fatigability of the caudate nucleus motor response was investigated in freely moving cats equipped with permanently implanted electrodes. Results were as follows: 1. (1) Under continuous stimulation, the caudate response fatigued in 10–20 min.
J M, Delgado +3 more
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The synaptic organization of the caudate nucleus
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1971The synaptic organization of the caudate nucleus appears to be homogeneous with no specialized groupings of axon terminals and postsynaptic profiles. The nerve terminals in the caudate nucleus fall into two size groups, one about 1 fim in diameter and the other about 5 /itn diameter.
J M, Kemp, T P, Powell
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Mitochondrial defect in Huntington's disease caudate nucleus
Annals of Neurology, 1996AbstractAlthough the Huntington's disease (HD) gene defect has been identified, the structure and function of the abnormal gene product and the pathogenetic mechanisms involved in producing death of selective neuronal populations are not understood.
M, Gu +5 more
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Caudate Nucleus Lesions Impair Spontaneous Alternation
Perceptual and Motor Skills, 1969I t has been reported that rats with caudate nucleus lesions rarely display the exploratory responses or the reactivity to novel environmental stimuli generally observed in intact animals ( 5 ) . TO investigate further the effect of caudate nucleus lesions on exploratory behavior, we tested caudectomized and control rats on spontaneous alternation.
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Dopamine transporter: Solubilization from dog caudate nucleus
Synapse, 1989Abstract3H‐GBR 12935 was used to label the digitonin‐solubilized dopamine transporter from dog caudate nucleus. Specific binding to soluble fractions was observed in dog caudate but was absent in rat cerebellum. Binding to the solubilized transporter sites was saturable and of high affinity (Bmax = 2.57 ± 0.60 pmol/mg protein, KD = 23.42 ± 2.24 nM, n =
R, Lew +3 more
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The cognitive functions of the caudate nucleus
Progress in Neurobiology, 2008The basal ganglia as a whole are broadly responsible for sensorimotor coordination, including response selection and initiation. However, it has become increasingly clear that regions of the basal ganglia are functionally delineated along corticostriatal lines, and that a modular conception of the respective functions of various nuclei is useful.
Jessica A, Grahn +2 more
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