Results 21 to 30 of about 511,225 (248)
REFINING THE MATERIAL SUBSTANCE: ARISTOTLE’S PROGRAM IN METAPHYSICS H1-5
Síntesis. Revista de Filosofía, 2018 En Metaph. Z17, Aristóteles toma un nuevo punto de partida (1041a6) en su discusión sobre la sustancia: la forma sustancial es principio y causa (1041a6-10, 1041b8), mientras que la materia es un elemento (1041b31) de las sustancias materiales. Además,
Fabián Mié
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Studium: Filosofía y Teología, 2014 El problema de Dios no ha sido considerado de una manera unívoca a través del tiempo. En esta reflexión no sólo han variado las respuestas, sino también los planteos del problema, cuyo objeto –Dios– es en sí mismo problemático, ya que no es objeto de ...
Dulce María Santiago
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Coleção Honoris Causa ; 3 [PDF]
, 1982 Speeches given when the title Doctor Honoris Causa was granted to the plastic artist Carybé - Héctor Júlio Páride Bernabó, on July 27, 1982, in the Main Hall of the Rectory Palace.Discursos proferidos quando da outorga do título Doutor Honoris Causa ao ...
Universidade Federal da Bahia
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
PlateletsImmune checkpoint inhibitors (ICIs) have transformed the treatment landscape for various malignancies, but they are associated with a range of immunerelated adverse events, including rare hematological complications.
Adolfo Fernández-Sánchez +6 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Haematologica, 2017 Immunoparesis or suppression of polyclonal immunoglobulins is a very common condition in newly diagnosed myeloma patients. However, the recovery of polyclonal immunoglobulins in the setting of immune reconstitution after autologous stem cell ...
Verónica González-Calle +18 more
doaj +1 more source