Results 31 to 40 of about 3,008 (215)

Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of Vixotrigine in Healthy Volunteers

open access: yesClinical and Translational Science, Volume 14, Issue 4, Page 1272-1279, July 2021., 2021
Neuropathic pain affects ~ 6.9–10% of the general population and leads to loss of function, anxiety, depression, sleep disturbance, and impaired cognition. Here, we report the safety, tolerability, and pharmacokinetics of a voltage‐dependent and use‐dependent sodium channel blocker, vixotrigine, currently under investigation for the treatment of ...
Himanshu Naik   +4 more
wiley   +1 more source

Three‐Year Outcomes After Dorsal Root Ganglion Stimulation in the Treatment of Neuropathic Pain After Peripheral Nerve Injury of Upper and Lower Extremities

open access: yesNeuromodulation: Technology at the Neural Interface, Volume 24, Issue 4, Page 700-707, June 2021., 2021
Abstract Objectives Traumatic peripheral nerve injuries (PNI) often result in severe neuropathic pain which typically becomes chronic, is recalcitrant to common analgesics, and is associated with sleep disturbances, anxiety, and depression. Pharmacological treatments proven to be effective against neuropathic pain are not well tolerated due to side ...
Michael Kretzschmar   +2 more
wiley   +1 more source

Dorsal root ganglion stimulation yielded higher treatment success rate for complex regional pain syndrome and causalgia at 3 and 12 months: a randomized comparative trial

open access: yesPain, 2016
Animal and human studies indicate that electrical stimulation of dorsal root ganglion (DRG) neurons may modulate neuropathic pain signals. ACCURATE, a pivotal, prospective, multicenter, randomized comparative effectiveness trial, was conducted in 152 ...
T. Deer   +27 more
semanticscholar   +1 more source

The Tourniquet Ischemia Test in the Diagnosis of Complex Regional Pain Syndrome

open access: yesPain Practice, Volume 21, Issue 3, Page 308-315, March 2021., 2021
Abstract Background The tourniquet ischemia test (IT) is a hitherto rarely used tool for the diagnostic work‐up of patients with suspected complex regional pain syndrome (CRPS). This analysis aims to determine the sensitivity and specificity of this test, and elucidate factors that can influence the test result.
Johann Lambeck   +3 more
wiley   +1 more source

Pain mechanisma in causalgia.

open access: yesJournal of Neurology, Neurosurgery and Psychiatry, 1976
S Sunderland
exaly   +2 more sources

Intra-Venous Lidocaine to Relieve Neuropathic Pain: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Neurology, 2019
Background: The prevalence of neuropathic pain is estimated to be between 7 and 10% in the general population. The efficacy of intravenous (IV) lidocaine has been studied by numerous clinical trials on patients with neuropathic pain.
Bo Zhu   +5 more
doaj   +1 more source

25, 50 and 75 years ago

open access: yes, 2023
ANZ Journal of Surgery, Volume 93, Issue 3, Page 466-468, March 2023.
Julian A. Smith
wiley   +1 more source

Simpatectomía: Opción Quirúrgica en el Tratamiento de la Causalgia y de la Distrofia Simpática Refleja

open access: yesRevista Colombiana de Cirugía, 2021
La causalgia y la distrofia simpática refleja son entidades poco frecuentes, caracterizadas por severo dolor localizado generalmente en el miembro superior. Su tratamiento es difícil, en especial cuando no se efectúa precozmente.
Pablo Alejandro Pinzón   +2 more
doaj  

Impacto da dor orofacial na qualidade de vida de portadores de câncer de boca e orofaringe [PDF]

open access: yesAudiology: Communication Research, 2022
RESUMO Objetivo investigar o impacto da dor orofacial na qualidade de vida de portadores de câncer de boca e orofaringe. Métodos trata-se de um estudo de corte transversal, observacional, descritivo, com amostra de conveniência.
Anderson Gonçalves Fernandes   +2 more
doaj   +1 more source

LETM presented with causalgia and ensued by sudden death

open access: yesBMC Neurology, 2017
BackgroundLongitudinally Extensive Transverse Myelitis LETM is a specific pattern of myelitis wherein at least three continuous vertebral segments are involved. Characteristically, it is a defining feature of neuromyelitis optica NMO.
R. Alsukhni   +4 more
semanticscholar   +1 more source

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